Evidence map›Paper›PMID 33109728›Full record

ArticleG3 (Bethesda, Md.)2020

High-Throughput Identification of Nuclear Envelope Protein Interactions in

Joseph M Varberg, Jennifer M Gardner, Scott McCroskey, Snehabala Saravanan, William D Bradford, Sue L Jaspersen

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. A multiomics atlas of theScience advances · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joseph M VarbergStowers Institute for Medical Research, Kansas City, Missouri.ORCID 0000-0002-5235-5896
Jennifer M GardnerStowers Institute for Medical Research, Kansas City, Missouri.
Scott McCroskeyStowers Institute for Medical Research, Kansas City, Missouri.
Snehabala SaravananStowers Institute for Medical Research, Kansas City, Missouri.
William D BradfordStowers Institute for Medical Research, Kansas City, Missouri.
Sue L JaspersenStowers Institute for Medical Research, Kansas City, Missouri, slj@stowers.org.ORCID 0000-0001-8312-7063
Stowers Institute for Medical Research · US

Funding

Assembly and Regulation of Yeast Spindle PolesR01GM121443 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI GERTON, JENNIFER L · 2017 to 2020
$1.3M
Defining the mechanisms of nuclear pore complex assembly in fission yeastF32GM133096 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI VARBERG, JOSEPH M · 2020 to 2021
$85k
NIGMS NIH HHS F32 GM133096NIGMS NIH HHS R01 GM121443
6 · The paper itself

Abstract

The nuclear envelope (NE) contains a specialized set of integral membrane proteins that maintain nuclear shape and integrity and influence chromatin organization and gene expression. Advances in proteomics techniques and studies in model organisms have identified hundreds of proteins that localize to the NE. However, the function of many of these proteins at the NE remains unclear, in part due to a lack of understanding of the interactions that these proteins participate in at the NE membrane. To assist in the characterization of NE transmembrane protein interactions we developed an arrayed library of integral and peripheral membrane proteins from the fission yeast

Indexed as

Saccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsMembrane ProteinsMitosisNuclear EnvelopeNuclear Pore Complex ProteinsNuclear ProteinsSaccharomyces cerevisiaeMembrane ProteinsNDC1 protein, S cerevisiaeNuclear Pore Complex ProteinsNuclear ProteinsSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteinshigh-throughput screeningmembrane proteinsnuclear envelopenuclear pore complexspindle pole body

Identifiers

PMID33109728
PMCPMC7718735
OpenAlexW3095310570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.