Evidence map›Paper›PMID 33109715›Full record

ArticleThe Journal of experimental biology2020

The relationship between longevity and diet is genotype dependent and sensitive to desiccation in

Andrew W McCracken, Eleanor Buckle, Mirre J P Simons

Open access · hybridAbstract read
In one paragraph

Article in The Journal of experimental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Mating-dependent lifespan cost of sterol depletion in maleProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Stochasticity in Dietary Restriction-Mediated Lifespan Outcomes inbioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Late-life shift in caloric intake affects fly metabolism and longevity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Amino Acid Availability Is Not Essential for Life-Span Extension by Dietary Restriction in the Fly.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew W McCrackenDepartment of Animal and Plant Sciences & Bateson Centre, The University of Sheffield, Sheffield S10 2TN, UK.ORCID 0000-0001-8889-6275
Eleanor BuckleDepartment of Animal and Plant Sciences & Bateson Centre, The University of Sheffield, Sheffield S10 2TN, UK.
Mirre J P SimonsDepartment of Animal and Plant Sciences & Bateson Centre, The University of Sheffield, Sheffield S10 2TN, UK m.simons@sheffield.ac.uk.ORCID 0000-0001-7406-7708
University of Sheffield · GB

Funding

British Heart FoundationWellcome TrustWellcome Trust 107400/Z/15/ZWellcome Trust 216405/Z/19/Z
6 · The paper itself

Abstract

Dietary restriction (DR) is a key focus in ageing research. Specific conditions and genotypes were recently found to negate lifespan extension by DR, questioning its universal relevance. However, the concept of dietary reaction norms explains why the effects of DR might be obscured in some situations. We tested the importance of dietary reaction norms by measuring longevity and fecundity on five diets in five genotypes, with and without water supplementation in female

Indexed as

Drosophila melanogasterLongevityAnimalsCaloric RestrictionDesiccationDietFemaleGenotypeAgeingDietary restrictionFruit flyOverfeedingReaction normStarvation

Identifiers

PMID33109715
PMCPMC7725603
OpenAlexW3095314624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.