Evidence map›Paper›PMID 33109639›Full record

ArticleBMJ open2020

Higher incidence of adverse events in isolated patients compared with non-isolated patients: a cohort study.

Fátima Jiménez-Pericás, María Teresa Gea Velázquez de Castro, María Pastor-Valero, Carlos Aibar Remón, Juan José Miralles, María Del Carmen Meyer García, Jesús Maria Aranaz Andrés

Erratum issuedAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Fátima Jiménez-PericásDepartment of Preventive Medicine and Public Health, Hospital Universitari San Juan de Alicante, Sant Joan d'Alacant, Spain jimper75@hotmail.com.ORCID 0000-0001-7393-8567
María Teresa Gea Velázquez de CastroDepartment of Preventive Medicine and Public Health, Hospital Universitari San Juan de Alicante, Sant Joan d'Alacant, Spain.
María Pastor-ValeroDepartment of Public Health, History of Science and Gynaecology, Universidad Miguel Hernández, Elche, Spain.
Carlos Aibar RemónPreventive Medicine and Public Health, Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain.
Juan José MirallesDepartment of Public Health, History of Science and Gynaecology, Universidad Miguel Hernández, Elche, Spain.
María Del Carmen Meyer GarcíaDepartment of Preventive Medicine and Public Health, Hospital Politécnico y Universitario La Fe, Valencia, Spain.
Jesús Maria Aranaz AndrésPreventive Medicine and Public Health, Hospital Universitario Ramon y Cajal, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether isolated patients admitted to hospital have a higher incidence of adverse events (AEs), to identify their nature, impact and preventability.

designProspective cohort study with isolated and non-isolated patients.

settingOne public university hospital in the Valencian Community (southeast Spain).

participantsWe consecutively collected 400 patients, 200 isolated and 200 non-isolated, age ≥18 years old, to match according to date of entry, admission department, sex, age (±5 years) and disease severity from April 2017 to October 2018. EXCLUSION CRITERIA: patients age <18 years old and/or reverse isolation patients. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome as the AE, defined according to the National Study of Adverse Effects linked to Hospitalisation (Estudio Nacional Sobre los Efectos Adversos) criteria. Cumulative incidence rates and AE incidence density rates were calculated.

resultsThe incidence of isolated patients with AEs 16.5% (95% CI 11.4% to 21.6%) compared with 9.5% (95% CI 5.4% to 13.6%) in non-isolated (p<0.03). The incidence density of patients with AEs among isolated patients was 11.8 per 1000 days/patient (95% CI 7.8 to 15.9) compared with 4.3 per 1000 days/patient (95% CI 2.4 to 6.3) among non-isolated patients (p<0.001). The incidence of AEs among isolated patients was 18.5% compared with 11% for non-isolated patients (p<0.09). Among the 37 AEs detected in 33 isolated patients, and the 22 AEs detected in 19 non-isolated patients, most corresponded to healthcare-associated infections (HAIs) for both isolated and non-isolated patients (48.6% vs 45.4%). There were significant differences with respect to the preventability of AEs, (67.6% among isolated patients compared with 52.6% among non-isolated patients).

conclusionsAEs were significantly higher in isolated patients compared with non-isolated patients, more than half being preventable and with HAIs as the primary cause. It is essential to improve training and the safety culture of healthcare professionals relating to the care provided to this type of patient.

Indexed as

Medical ErrorsAdolescentCohort StudiesHumansIncidenceProspective StudiesSpainhealth & safetypreventive medicinepublic healthquality in health carerisk management

Identifiers

PMID33109639
PMCPMC7592267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.