Evidence map›Paper›PMID 33109609›Full record

ArticleThe Journal of biological chemistry2020

ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).

Balaji Banoth, Shraddha Tuladhar, Rajendra Karki, Bhesh Raj Sharma, Benoit Briard, Sannula Kesavardhana, Amanda Burton, Thirumala-Devi Kanneganti

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 221 citations in OpenAlex.

  1. Review
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  5. Review
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  10. Review
  11. Role of PANoptosis in intestinal diseases and its therapeutic implications.Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  12. Article
  13. Article
  14. Apoptotic body-encapsulated zinc-dopedMaterials today. Bio · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Balaji BanothDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Shraddha TuladharDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Rajendra KarkiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Bhesh Raj SharmaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Benoit BriardDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Sannula KesavardhanaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Amanda BurtonDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Thirumala-Devi KannegantiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: Thirumala-Devi.Kanneganti@StJude.org.
St. Jude Children's Research Hospital · US

Funding

Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancerR35CA253095 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2020 to 2026
$7.0M
Role of NLR Inflammasomes in Autoinflammatory Diseases and Host DefenseR01AR056296 · NIAMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2008 to 2022
$5.9M
The Non-Inflammasome NLRs in Immunity and Host defenseR01AI124346 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2016 to 2026
$5.8M
Inflammatory Caspases in Innate Immunity and InflammationR37AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2017 to 2026
$4.9M
Inflammatory Caspases in Innate Immunity and InflammationR01AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2012 to 2016
$2.2M
NCI NIH HHS R35 CA253095NIAID NIH HHS R01 AI101935NIAID NIH HHS R01 AI124346NIAID NIH HHS R37 AI101935NIAMS NIH HHS R01 AR056296
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisNecroptosisPyroptosisAnimalsFungiHumansInflammasomesInflammationMacrophagesMiceMice, Inbred C57BLRNA-Binding ProteinsInflammasomesRNA-Binding ProteinsZBP1 protein, humanZbp1 protein, mouseapoptosisAspergillus fumigatusCandida albicanscaspase-1caspase-3caspase-7caspase-8cell deathfungigasdermin Dhost defenseinfectioninfectious diseaseinflammasomeMLKLnecroptosisPANoptosisPANoptosomepyroptosisRIPK3ZBP1

Identifiers

PMID33109609
PMCPMC7939383
OpenAlexW3096272935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.