Evidence map›Paper›PMID 33109264›Full record

ArticleJournal of medical case reports2020

Small cell carcinoma of the prostate after low-dose-rate brachytherapy: a case report.

Eva Van Bos, Peter Dekuyper, Charlotte Gabriel, Marjan Waterloos, Anthony Van Baelen, Stefan Huybrechts, Filip Ameye, Antoon Lambrecht, Christof Vulsteke, Charlotte Soenens

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Eva Van BosDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium. eva.vanbos@azmmsj.be.
Peter DekuyperDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
Charlotte GabrielDepartment of Pathology, AZ Maria Middelares, Ghent, Belgium.
Marjan WaterloosDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
Anthony Van BaelenDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
Stefan HuybrechtsDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
Filip AmeyeDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
Antoon LambrechtDepartment of Radiotherapy, AZ Groeninge, Kortrijk, Belgium.
Christof VulstekeDepartment of Oncology, AZ Maria Middelares, Ghent, Belgium.
Charlotte SoenensDepartment of Urology, AZ Maria Middelares, Buitenring-Sint-Denijs 30, 9000, Ghent, Belgium.
AZ Maria Middelares · BEAZ Groeninge · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall cell carcinoma of the prostate is a rare condition with important differences from prostatic adenocarcinoma in terms of clinical and prognostic characteristics. A low prostate-specific antigen and a symptomatic patient, including paraneoplastic symptoms, characterize small cell carcinoma of the prostate. Diagnosis is made on the basis of prostate biopsy, and fluorodeoxyglucose positron emission tomography/computed tomography is often used for staging because up to 60% of patients present with de novo metastatic disease. Patients with metastatic disease are usually treated with platinum-based cytotoxic chemotherapy regimens similar to those used for small cell carcinoma of the lung. However, prognosis remains poor, with a median overall survival of 9 to 17 months despite therapy. CASE PRESENTATION: This report describes a case of an 80-year-old Caucasian patient with lymph node and bone metastatic small cell carcinoma of the prostate following low-dose-rate brachytherapy for a low-risk prostate carcinoma and treated with chemotherapy and immunotherapy.

conclusionLow-dose-rate brachytherapy might be an etiology of small cell prostate cancer.

Indexed as

AdenocarcinomaBrachytherapyCarcinoma, Small CellLung NeoplasmsProstatic NeoplasmsAged, 80 and overHumansMaleProstateProstate-Specific AntigenProstate-Specific AntigenChemotherapyImmunotherapyIonizing radiotherapyLow-dose-rate brachytherapyProstate cancerSmall cell carcinoma

Identifiers

PMID33109264
PMCPMC7592557
OpenAlexW3094951107

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.