Evidence map›Paper›PMID 33109259›Full record

ArticleJournal of orthopaedic surgery and research2020

Predictive value of adipose to muscle area ratio based on MRI at knee joint for postoperative functional outcomes in elderly osteoarthritis patients following total knee arthroplasty.

Guanglei Zhao, Changquan Liu, Kangming Chen, Feiyan Chen, Jinyang Lyu, Jie Chen, Jingsheng Shi, Gangyong Huang, Yibing Wei, Siqun Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Guanglei ZhaoDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Changquan LiuDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Kangming ChenDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Feiyan ChenDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jinyang LyuDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jie ChenDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jingsheng ShiDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Gangyong HuangDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Yibing WeiDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Siqun WangDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Jun XiaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai, 200040, China. hudbt17089@gmail.com.
Fudan University · CNHuashan Hospital · CN

Funding

The Ministry of Science and Technology of China 2020YFC2002800
6 · The paper itself

Abstract

backgroundThe current research used a new index-adipose to muscle area ratio (AMR)-to measure fatness compared with body mass index (BMI) in elderly osteoarthritis (OA) patients following total knee arthroplasty. Our study aimed to test the relationship between the two indexes (AMR and BMI) and to examine whether AMR was a predictive factor of patient-reported outcome measures (PROMS) for elderly OA patients following total knee arthroplasty (TKA).

methodsThe retrospective data of 78 OA patients (older than 60 years) following TKA was included in our study. Clinical features of patients included age, BMI, sex, AMR, side of the implant, time of follow-up, complications, the Knee Society Score (KSS score), and the Hospital for Special Surgery knee score (HSS score). The area of adipose tissue and muscle tissue was measured on the cross section (supra-patella, midline of the patella, joint line of the knee) of the knee magnetic resonance imaging (MRI). AMR was calculated as the average of adipose to muscle area ratio at the three levels. The Pearson correlation analysis, simple linear regression, and multiple linear regression were used to study the relationship between BMI, AMR, and PROMS (KSS total-post score and HSS-post score) in the study.

resultsOf all patients, the mean (± standard deviations (SD)) of age was 67.78 ± 4.91 years. For BMI and AMR, the mean (± SD) were 26.90 ± 2.11 and 2.36 ± 0.69, respectively. In Pearson correlation analysis, BMI had a good correlation with AMR (r = 0.56, p = 0.000), and AMR (r = - 0.37, p = 0.001, HSS-post score; r = - 0.43, p = 0.000, KSS total-post score) had better correlations with PROMS postoperatively compared with BMI (r = - 0.27, p = 0.019, HSS-post score; r = - 0.33, p = 0.003, KSS total-post score). In multivariate linear regression analysis, AMR was negatively correlated with KSS total-post score as well as HSS-post score, while BMI was not. As for patients with complications, AMR values were between the 3rd quartile and 4th quartile of the AMR value in the entire study cohort.

conclusionsIn this study, the new obesity evaluation indicator-AMR, which was well related with BMI, was found to be a predictor of PROMS (KSS total-post score and HSS-post score) in elderly OA patients following TKA.

Indexed as

Arthroplasty, Replacement, KneeMagnetic Resonance ImagingPatient Reported Outcome MeasuresAdipose TissueAgedBody Mass IndexFemaleHumansKnee JointMaleMiddle AgedMuscle, SkeletalOsteoarthritis, KneePredictive Value of TestsRetrospective StudiesAdipose to muscle area ratio (AMR)Body mass index (BMI)Osteoarthritis (OA)Patient-reported outcome measures (PROMS)PredictorTotal knee arthroplasty (TKA)

Identifiers

PMID33109259
PMCPMC7590798
OpenAlexW3095294944

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.