ArticleBMC evolutionary biology2020
Whole-genome resequencing provides insights into the evolution and divergence of the native domestic yaks of the Qinghai-Tibet Plateau.
Article in BMC evolutionary biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Genome-wide detection and genomic selection based on genotype-by-environment interaction-associated signals for yak coat color.BMC genomics · 2026Article
- Genome-Wide Association Study and Whole-Genome Resequencing Reveal Key lincRNA and Candidate Gene for Polled Phenotype in Yak.Animals : an open access journal from MDPI · 2026Article
- Genome characteristics and identification of reproduction-related genes in Southwest meat goats.BMC genomics · 2026Article
- Mitochondrial Introgression With Potential Functional Effects in North American Yak.Ecology and evolution · 2025Article
- A 14-bp motif in the KIT active promoter region is critical for melanin accumulation in yaks, mice, and humans.BMC biology · 2025Article
- Comprehensive genomic analysis of genetic diversity, body size, and origins of the Hetian Gray donkey.BMC genomics · 2025Article
- Transcriptomics Reveals the Differences in mRNA Expression Patterns in Yak Uterus of Follicular, Luteal, and Pregnant Phases.Animals : an open access journal from MDPI · 2025Article
- Leveraging Whole-Genome Resequencing to Uncover Genetic Diversity and Promote Conservation Strategies for Ruminants in Asia.Animals : an open access journal from MDPI · 2025Review
- Dissecting genomes of multiple yak populations: unveiling ancestry and high-altitude adaptation through whole-genome resequencing analysis.BMC genomics · 2025Article
- Identifying low-density, ancestry-informative SNP markers through whole genome resequencing in Indian, Chinese, and wild yak.BMC genomics · 2024Article
- Whole genome resequencing revealed genomic variants and functional pathways related to adaptation in Indian yak populations.Animal biotechnology · 2024Article
- Comparative Analysis of the Potential Adaptability of Tibetan Dzo and Yellow Cattle Based on Blood Indices, Metabolites, and Fecal Microbiota.Animals : an open access journal from MDPI · 2024Article
- Pangenome and multi-tissue gene atlas provide new insights into the domestication and highland adaptation of yaks.Journal of animal science and biotechnology · 2024Article
- Whole-genome resequencing reveals the uniqueness of Subei yak.Journal of animal science · 2024Article
- Whole-genome resequencing reveals genetic diversity, differentiation, and selection signatures of yak breeds/populations in southwestern China.Frontiers in genetics · 2024Article
- Evidence for early domestic yak, taurine cattle, and their hybrids on the Tibetan Plateau.Science advances · 2023Article
- Genome Variation Map of Domestic Qinghai-Tibet Plateau Yaks by SLAF-Seq Reveals Genetic Footprint during Artificial Selection.Animals : an open access journal from MDPI · 2023Article
- Evolutionary origin of genomic structural variations in domestic yaks.Nature communications · 2023Article
- Identification of Candidate Genes Associated with Yak Body Size Using a Genome-Wide Association Study and Multiple Populations of Information.Animals : an open access journal from MDPI · 2023Article
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14 authors.
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Abstract
backgroundOn the Qinghai-Tibet Plateau, known as the roof ridge of the world, the yak is a precious cattle species that has been indispensable to the human beings living in this high-altitude area. However, the origin of domestication, dispersal route, and the divergence of domestic yaks from different areas are poorly understood.
resultsHere, we resequenced the genome of 91 domestic yak individuals from 31 populations and 1 wild yaks throughout China. Using a population genomics approach, we observed considerable genetic variation. Phylogenetic analysis suggested that the earliest domestications of yak occurred in the south-eastern QTP, followed by dispersal to the west QTP and northeast to SiChuang, Gansu, and Qinghai by two routes. Interestingly, we also found potential associations between the distribution of some breeds and historical trade routes such as the Silk Road and Tang-Tibet Ancient Road. Selective analysis identified 11 genes showing differentiation between domesticated and wild yaks and the potentially positively selected genes in each group were identified and compared among domesticated groups. We also detected an unbalanced pattern of introgression among domestic yak, wild yak, and Tibetan cattle.
conclusionsOur research revealed population genetic evidence for three groups of domestic yaks. In addition to providing genomic evidence for the domestication history of yaks, we identified potential selected genes and introgression, which provide a theoretical basis and resources for the selective breeding of superior characters and high-quality yak.
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