Evidence map›Paper›PMID 33108691›Full record

ArticleJournal of cellular and molecular medicine2020

Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate.

Lan Ma, Shu Lou, Ziyue Miao, Siyue Yao, Xin Yu, Shiyi Kan, Guirong Zhu, Fan Yang, Chi Zhang, Weibing Zhang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Skeletal Class III Malocclusion Is Associated withInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Lan MaJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.ORCID 0000-0003-3593-5626
Shu LouJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Ziyue MiaoJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Siyue YaoJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Xin YuJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Shiyi KanJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Guirong ZhuJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Fan YangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Chi ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Weibing ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Meilin WangDepartment of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
Lin WangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Yongchu PanJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNStomatology Hospital · CNJiangsu Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although several genome-wide association studies (GWAS) of non-syndromic cleft lip with or without cleft palate (NSCL/P) have been reported, more novel association signals are remained to be exploited. Here, we performed an in-depth analysis of our previously published Chinese GWAS cohort study with replication in an extra dbGaP case-parent trios and another in-house Nanjing cohort, and finally identified five novel significant association signals (rs11119445: 3' of SERTAD4, P = 6.44 × 10

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseQuantitative Trait LociAllelesAnimalsCase-Control StudiesCleft LipCleft PalateComputational BiologyDisease Models, AnimalFemaleGene EditingGenome-Wide Association StudyGenotypeHumansMaleassociation signalsmolecular geneticsorofacial cleftssusceptibilityzebrafish

Identifiers

PMID33108691
PMCPMC7754035
OpenAlexW3096585865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.