Evidence map›Paper›PMID 33108619›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2021

The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids.

Michał Ciebiera, Mohamed Ali, Lillian Prince, Stanisław Zgliczyński, Grzegorz Jakiel, Ayman Al-Hendy

Open access · hybridAbstract readReview
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Observational
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Michał CiebieraSecond Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, ul. Cegłowska 80, 01-809, Warsaw, Poland. michal.ciebiera@gmail.com.ORCID 0000-0001-5780-5983
Mohamed AliDepartment of Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Lillian PrinceBiological Sciences Division: Public Health Sciences, University of Chicago, Chicago, IL, USA.
Stanisław ZgliczyńskiDepartment of Internal Diseases and Endocrinology, Central Teaching Clinical Hospital, Medical University of Warsaw, Warsaw, Poland.
Grzegorz JakielFirst Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, Warsaw, Poland.
Ayman Al-HendyDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL, USA.
Ain Shams University · EGChicago Department of Public Health · USMedical University of Warsaw · PLPostgraduate School of Molecular Medicine · PLUniversity of Chicago · USUniversity of Illinois Chicago · US

Funding

Training the Trainers: Building Institutional Data Science Capacity to Support Health Disparities ResearchU54MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI Kevin Sean Kimbro · 2018 to 2026
$47.6M
TRANSPLANTATION OF EXOSOMES FROM HYPOXIA-PRECONDITIONED ADIPOSE-DERIVED STEM CELLS PROMOTES ANGIOGENESIS IN ISCHEMIC HEARTG12MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI BOND, VINCENT C · 2012 to 2017
$18.4M
Investigating the effectiveness of COVID-19 testing choices, community engagement, and culturally-embedded mHealth literacy delivery in a medically-underserved, community-based sampleR01ES028615 · NIEHS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AL-HENDY, AYMAN, WALKER, CHERYL L. · 2017 to 2022
$5.0M
Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroidsR01HD094378 · NICHD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI AL-HENDY, AYMAN, BOYER, THOMAS G · 2018 to 2022
$4.2M
Mechanisms of actions(s) of simvastatin in uterine leiomyomaR01HD094380 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BORAHAY, MOSTAFA A. · 2018 to 2022
$4.0M
Implications of MTHFR Polymorphisms in Women receiving a Combination of Green Tea Extract and Fertility Promoting Drugs on Serum Folate LevelsR01HD100367 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AL-HENDY, AYMAN, GONZALEZ, FRANK · 2019 to 2023
$1.7M
NICHD NIH HHS R01 HD094378NICHD NIH HHS R01 HD094380NICHD NIH HHS R01 HD100367NIEHS NIH HHS R01 ES028615NIMHD NIH HHS G12 MD007602NIMHD NIH HHS U54 MD007602
6 · The paper itself

Abstract

Uterine fibroids (UFs) are benign tumors originating from smooth muscle cells and are considered a common pathology that affects numerous women which is a notable socio-economic problem. Several UF risk factors have been identified including black race, obesity, and vitamin D deficiency. Vitamin D is steroid compound with pleiotropic effects on the human body. Vitamin D deficiency is a major public health concern worldwide. Several studies have shown that the majority of UF patients experienced hypovitaminosis D. In addition, sufficient vitamin D serum levels are associated with the reduced risk of UFs. In this review, we present available data highlighting the importance of measuring vitamin D serum levels in women with UFs and women at a high risk for UF development. We proposed a preliminary clinical instruction of 25-hydroxyvitamin D measurements and vitamin D supplementation for clinicians who are involved in the treatment of patients with UFs. Achieving sufficient serum levels of vitamin D might be of interest in patients with UFs. Screening, supplementation, treatment guidelines, and public health strategies for vitamin D deficiency in women with UFs as well as women at a high risk of UF development might be of potential importance as well.

Indexed as

FemaleHumansLeiomyomaRisk FactorsUterine NeoplasmsVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin D25-hydroxyvitamin DLeiomyomaRisk factorSerum levelUterine fibroidVitamin D

Identifiers

PMID33108619
PMCPMC8262605
OpenAlexW3095236704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.