Evidence map›Paper›PMID 33108470›Full record

ArticleClinical neuroradiology2021

Approaching the Boundaries of Endovascular Treatment in Acute Ischemic Stroke : Multicenter Experience with Mechanical Thrombectomy in Vertebrobasilar Artery Branch Occlusions.

Hanna Styczen, Sebastian Fischer, Leonard Ll Yeo, Benjamin Yong-Qiang Tan, Christoph J Maurer, Ansgar Berlis, Nuran Abdullayev, Christoph Kabbasch, Andreas Kastrup, Panagiotis Papanagiotou and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 4 countries.

Hanna StyczenInstitute for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstraße 55, 45122, Essen, Germany. hanna.styczen@uk-essen.de.ORCID http://orcid.org/0000-0002-9623-4156
Sebastian FischerDepartment of Radiology, Neuroradiology and Nuclear Medicine, Knappschaftskrankenhaus Langendreer, Ruhr-University Bochum, Bochum, Germany.
Leonard Ll YeoDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Benjamin Yong-Qiang TanDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Christoph J MaurerDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany.
Ansgar BerlisDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany.
Nuran AbdullayevDepartment of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany.
Christoph KabbaschDepartment of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany.
Andreas KastrupDepartment of Neurology, Klinikum Bremen, Bremen, Germany.
Panagiotis PapanagiotouDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Bremen-Mitte, Bremen, Germany.
Christin ClajusDepartment of Diagnostic and Interventional Radiology and Neuroradiology, Helios General Hospital Erfurt, Erfurt, Germany.
Donald LobsienDepartment of Diagnostic and Interventional Radiology and Neuroradiology, Helios General Hospital Erfurt, Erfurt, Germany.
Eike PiechowiakUniversity Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.
Johannes KaesmacherUniversity Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.
Volker MausDepartment of Radiology, Neuroradiology and Nuclear Medicine, Knappschaftskrankenhaus Langendreer, Ruhr-University Bochum, Bochum, Germany.
Helios Klinikum Erfurt · DENational University of Singapore · SGUniversitätsklinikum Knappschaftskrankenhaus Bochum · DEUniversity Hospital Augsburg · DEUniversity Hospital Cologne · DEUniversity of Bern · CHEssen University Hospital · DEKlinikum Bremen-Mitte · DENational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLittle is known about catheter-based endovascular treatment of vertebrobasilar artery branch occlusion (VEBABO) in acute ischemic stroke (AIS). Nonetheless, the experience of mechanical thrombectomy (MT) in distal small sized arteries of the anterior circulation seems promising in AIS. In this multicenter study, we report the feasibility, efficacy and safety of MT in VEBABO.

methodsRetrospective analysis of consecutive AIS patients treated with MT due to VEBABO including posterior and anterior inferior cerebellar artery (PICA, AICA) and superior cerebellar artery (SCA) occlusions at seven tertiary care centers between January 2013 and May 2020. Baseline demographics and angiographic outcomes including recanalization success of the affected cerebellar arteries and procedural complications were recorded. Clinical outcomes were evaluated by the modified Rankin scale (mRS) at discharge and 90 days.

resultsOut of 668 endovascularly treated posterior circulation strokes we identified 16 (0.02%) cases with MT for VEBABO. Most frequently, MT of the SCA was done (13/16, 81%). Most VEBABOs occurred after MT of initial basilar/posterior cerebral artery occlusion (9/16, 56%). In 10/16 (63%) procedures, the affected VEBABO was successfully recanalized. Out of four patients three (75%) with isolated VEBABO had benefited from endovascular therapy. Subarachnoid hemorrhage was observed in 3/16 (19%) procedures. The rate of favorable outcome (mRS ≤2) was 40% at discharge and 47% at 90-day follow-up. Mortality was 13% (2/15).

conclusionThe use of MT for VEBABO is rare but appears to be feasible and effective; however, the comparatively high rate of procedure-related hemorrhage highlights that the indications for MT in these occlusion sites should be carefully weighed up.

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeVertebrobasilar InsufficiencyBasilar ArteryHumansRetrospective StudiesThrombectomyTreatment OutcomeBasilar arteryMechanical thrombectomyPosterior circulationVertebral arteryVertebrobasilar branch occlusion

Identifiers

PMID33108470
OpenAlexW3095213776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.