Evidence map›Paper›PMID 33108397›Full record

ArticlePloS one2020

Pregnancy complications and maternal birth outcomes in women with intellectual and developmental disabilities in Wisconsin Medicaid.

Eric Rubenstein, Deborah B Ehrenthal, David C Mallinson, Lauren Bishop, Hsiang-Huo Kuo, Maureen Durkin

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Maternal mental disorders and neonatal outcomes: Danish population-based cohort study.The British journal of psychiatry : the journal of mental science · 2025
    Article
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  11. Article
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  14. Review
  15. Article
  16. Maternal Health Experiences of Black Deaf and Hard of Hearing Women in the United States.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric RubensteinWaisman Center, University of Wisconsin Madison, Madison, WI, United States of America.ORCID 0000-0002-9146-4497
Deborah B EhrenthalDepartment of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
David C MallinsonDepartment of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.ORCID 0000-0003-1069-6040
Lauren BishopWaisman Center, University of Wisconsin Madison, Madison, WI, United States of America.
Hsiang-Huo KuoDepartment of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Maureen DurkinWaisman Center, University of Wisconsin Madison, Madison, WI, United States of America.
University of Wisconsin–Madison · USBoston University · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Institutional Career Development CoreKL2TR002374 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Bo Liu, Marin Leigh Schweizer · 2017 to 2026
$9.7M
Diversity supplementT32HD007014 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine J. Curtis · 1985 to 2026
$6.8M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 2016 to 2020
$6.0M
PREGNANCY RATES, RISK FACTORS, AND CHILD AND MOTHER OUTCOMES FOR WOMEN WITH INTELLECTUAL AND DEVELOPMENTAL DISABILITIES IN WISCONSIN.R03HD099619 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI RUBENSTEIN, ERIC S · 2019 to 2020
$160k
NCATS NIH HHS KL2 TR002374NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NICHD NIH HHS R03 HD099619NICHD NIH HHS T32 HD007014NICHD NIH HHS U54 HD090256
6 · The paper itself

Abstract

backgroundWomen with intellectual and developmental disabilities (IDD) may face greater risk for poor pregnancy outcomes. Our objective was to examine risk of maternal pregnancy complications and birth outcomes in women with IDD compared to women without IDD in Wisconsin Medicaid, from 2007-2016.

methodsData were from the Big Data for Little Kids project, a data linkage that creates an administrative data based cohort of mothers and children in Wisconsin. Women with ≥1 IDD claim the year before delivery were classified as having IDD. Common pregnancy complications and maternal birth outcomes were identified from the birth record. We calculated risk ratios (RR) using log-linear regression clustered by mother. We examined outcomes grouped by IDD-type and explored interaction by race.

resultsOf 177,691 women with live births, 1,032 (0.58%) had an IDD claim. Of 274,865 deliveries, 1,757 were to mothers with IDD (0.64%). Women with IDD were at greater risk for gestational diabetes (RR: 1.28, 95% CI: 1.0, 1.6), gestational hypertension (RR: 1.22, 95% CI: 1.0, 1.5), and caesarean delivery (RR 1.32, 95% CI: 1.2, 1.4) compared to other women. Adjustment for demographic covariates did not change estimates. Women with intellectual disability were at highest risk of gestational hypertension. Black women with IDD were at higher risk of gestational hypertension than expected under a multiplicative model.

conclusionsWomen with IDD have increased risk of pregnancy complications and adverse outcomes in Wisconsin Medicaid. Results were robust to adjustment. Unique patterns by IDD types and Black race warrant further exploration.

Indexed as

MedicaidPregnancy OutcomeAdolescentAdultDevelopmental DisabilitiesFemaleHumansIntellectual DisabilityOdds RatioParturitionPregnancyPregnancy ComplicationsRacial GroupsUnited StatesWisconsinYoung Adult

Identifiers

PMID33108397
PMCPMC7591078
OpenAlexW3096237096

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.