ArticlePloS one2020
Transition from pediatric to adult care for adolescents living with HIV in South Africa: A natural experiment and survival analysis.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Retention in Care After Transition to Adult Care for Adolescents and Young Adults With HIV: A Systematic Review and Meta-Analysis.International journal of public health · 2025Pooled it
- Systematic Review of mHealth Interventions for Adolescent and Young Adult HIV Prevention and the Adolescent HIV Continuum of Care in Low to Middle Income Countries.AIDS and behavior · 2023Pooled it
- Systematic Review of mHealth Interventions for Adolescent and Young Adult HIV Prevention and the Adolescent HIV Continuum of Care in Low to Middle Income Countries.AIDS and behavior · 2023Pooled it
- Interventions addressing the adolescent HIV continuum of care in South Africa: a systematic review and modified Delphi analysis.BMJ open · 2022Pooled it
- Interactive Transition Support for Adolescents Living with HIV Comparing Virtual and In-person delivery (InTSHA VIP): a stepped-wedge, cluster-randomised trial in South Africa.BMC health services research · 2026Trial
- Trial
- Estimating the costs of adolescent HIV care visits and an intervention to facilitate transition to adult care in Kenya.PloS one · 2024Trial
- Transition to independent care for youth living with HIV: a cluster randomised clinical trial.The lancet. HIV · 2022Trial
- Effective Handling of Health Care Transition for Young People Living With HIV: A Consensus of Experts in Thailand Using Modified Delphi Method.The Journal of the Association of Nurses in AIDS Care : JANAC · 2026Article
- Post-transition Care Retention and Viral Suppression Outcomes Among Youth Living with HIV in South Carolina: A Real-World Data Research.AIDS and behavior · 2026Article
- Prevalence, associated factors and geospatial patterns of HIV drug resistance in South Africa among the virally unsuppressed adults: updated results from the 2017 national HIV household survey.BMC public health · 2026Article
- Article
- Health services' responses to transitioning adolescents to adult HIV care in South Africa.African journal of primary health care & family medicine · 2025Article
- Long-Term Outcomes of Young Adults With Perinatal Human Immunodeficiency Virus (HIV) Infection in the United States and Puerto Rico.Open forum infectious diseases · 2025Article
- From Pediatric to Adult HIV Care: What Works to Keep Adolescents Engaged-A Systematic Review of Transition Strategies.Tropical medicine and infectious disease · 2025Review
- Preferences of South African Adolescents Living with HIV in the Western Cape Province Regarding the Use of Digital Technology for Self-Management.International journal of environmental research and public health · 2025Article
- "I-We-I": Visualizing Adolescents' Perceptions and Apprehension to Transition to Adult HIV Care at a Supportive Transition Facility in the Cape Town Metropole, South Africa.Tropical medicine and infectious disease · 2025Article
- Transition to Adult Care for Young People Living with HIV.Current HIV/AIDS reports · 2025Review
- Article
- Transition of adolescents from paediatric to adult HIV care in South Africa: A policy review.Southern African journal of HIV medicine · 2025Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveTo determine rates of retention and viral suppression among adolescents living with perinatally-acquired HIV who remained in pediatric care compared to those who transitioned to adult care.
methodsWe evaluated a natural experiment involving adolescents living with perinatally-acquired HIV who were attending a government-supported antiretroviral clinic in KwaZulu-Natal, South Africa. Prior to 2011, all adolescents transitioned to adult care at 12 years of age. Due to a policy change, all adolescents were retained in pediatric care after 2011. We analyzed adolescents two years before and two years after this policy change. Outcomes were retention in care and HIV viral suppression one year after transition to adult care or the 13th birthday if remaining in pediatric care.
resultsIn the natural experiment, 180 adolescents who turned 12 years old between 2011 and 2014 were evaluated; 35 (20%) transitioned to adult care under the old policy and 145 (80%) remained in pediatric care under the new policy. Adolescents who transitioned to the adult clinic had lower rates of retention in care (49%; 17/35) compared to adolescents remaining in the pediatric clinic (92%; 134/145; p<0.001). Retention in care was lower (ARR 0.59; 95%CI 0.43-0.82; p = 0.001) and viral suppression was similar (ARR = 1.06, 95%CI 0.89-1.26; p = 0.53) for adolescents who transitioned to adult care compared to adolescents remaining in pediatric care.
conclusionAdolescents living with perinatally-acquired HIV appear to have higher retention in care when cared for in pediatric clinics compared to adult clinics. Longer-term follow-up is needed to fully assess viral suppression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.