Evidence map›Paper›PMID 33108274›Full record

ArticleeLife2020

The

Nicole L Nuckolls, Anthony C Mok, Jeffrey J Lange, Kexi Yi, Tejbir S Kandola, Andrew M Hunn, Scott McCroskey, Julia L Snyder, María Angélica Bravo Núñez, Melainia McClain and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026
    Article
  3. Evolutionary persistence and divergence of thebioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Functional constraints ofbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Proliferation and dissemination of killer meiotic drive loci.Current opinion in genetics & development · 2023
    Review
  11. Article
  12. Article
  13. Enforcement of Postzygotic Species Boundaries in the Fungal Kingdom.Microbiology and molecular biology reviews : MMBR · 2022
    Review
  14. Article
  15. TheeLife · 2022
    Article
  16. Article
  17. Article
  18. Molecular Mechanisms and Evolutionary Consequences of Spore Killers in Ascomycetes.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Nicole L NuckollsStowers Institute for Medical Research, Kansas City, United States.
Anthony C MokStowers Institute for Medical Research, Kansas City, United States.
Jeffrey J LangeStowers Institute for Medical Research, Kansas City, United States.
Kexi YiStowers Institute for Medical Research, Kansas City, United States.
Tejbir S KandolaStowers Institute for Medical Research, Kansas City, United States.
Andrew M HunnStowers Institute for Medical Research, Kansas City, United States.
Scott McCroskeyStowers Institute for Medical Research, Kansas City, United States.
Julia L SnyderStowers Institute for Medical Research, Kansas City, United States.
María Angélica Bravo NúñezStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0002-6554-8814
Melainia McClainStowers Institute for Medical Research, Kansas City, United States.
Sean A McKinneyStowers Institute for Medical Research, Kansas City, United States.
Christopher WoodStowers Institute for Medical Research, Kansas City, United States.
Randal HalfmannStowers Institute for Medical Research, Kansas City, United States.
Sarah E ZandersStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0003-1867-986X
Stowers Institute for Medical Research · US

Funding

Models of Selfishness: Molecular and Evolutionary Analyses of the Wtf Meiotic DriversDP2GM132936 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2018 to 2018
$2.5M
Contributions of protein aggregation to gene regulation and phenotypic diversityDP5OD009152 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI HALFMANN, RANDAL ARTHUR · 2011 to 2015
$1.6M
Mechanisms of meiotic drive and the functional consequences of rapid genome evolutionR00GM114436 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2016 to 2018
$747k
Conflict-driven aneuploidy and genomic instability caused by meiotic proteinsK00CA234523 · NCI · HARVARD UNIVERSITY · PI BRAVO NUNEZ, MARIA ANGELICA · 2020 to 2020
$86k
Conflict-driven aneuploidy and genomic instability caused by meiotic proteinsF99CA234523 · NCI · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI BRAVO NUNEZ, MARIA ANGELICA · 2018 to 2019
$59k
Investigating the mechanism of wtf killer meiotic driversF31HD097974 · NICHD · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI NUCKOLLS, NICOLE · 2018 to 2020
$49k
NCI NIH HHS F99 CA234523NCI NIH HHS K00 CA234523NICHD NIH HHS F31 HD097974NIGMS NIH HHS DP2 GM132936NIGMS NIH HHS R00 GM114436NIH HHS DP5 OD009152
6 · The paper itself

Abstract

Meiotic drivers are parasitic loci that force their own transmission into greater than half of the offspring of a heterozygote. Many drivers have been identified, but their molecular mechanisms are largely unknown. The

Indexed as

Genes, FungalCell DeathProtein AggregatesSaccharomyces cerevisiaeSchizosaccharomycesProtein Aggregatesautophagycell biologyevolutionary biologymeiosisMeiotic driveprotein aggregationproteostasisS. cerevisiaeS. pombewtf

Identifiers

PMID33108274
PMCPMC7591262
OpenAlexW3097079046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.