Evidence map›Paper›PMID 33107824›Full record

ArticleeLife2020

Arpan C Ghosh, Sudhir Gopal Tattikota, Yifang Liu, Aram Comjean, Yanhui Hu, Victor Barrera, Shannan J Ho Sui, Norbert Perrimon

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. A Landscape ofBiology · 2026
    Review
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  7. Frontiers in endocrinology · 2026
    Article
  8. Article
  9. ThebioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arpan C GhoshDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0001-6553-938X
Sudhir Gopal Tattikota *Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0003-0318-5533
Yifang Liu *Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.
Aram ComjeanDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.
Yanhui HuDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.
Victor BarreraHarvard Chan Bioinformatics Core, Harvard T.H. Chan School of Public Health, Boston, United States.ORCID http://orcid.org/0000-0003-0590-4634
Shannan J Ho SuiHarvard Chan Bioinformatics Core, Harvard T.H. Chan School of Public Health, Boston, United States.
Norbert PerrimonDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, United States.
Harvard University · USHoward Hughes Medical Institute · US

Funding

Tuberous Sclerosis-Pathway and PathogenesisP01CA120964 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI David J. Kwiatkowski · 2007 to 2026
$35.9M
Characterization of the Insulin to Autophagy Pathway in MusclesR01AR057352 · NIAMS · HARVARD MEDICAL SCHOOL · PI NORBERT PERRIMON · 2010 to 2026
$8.2M
American Heart Association 18POST33990414Howard Hughes Medical InstituteNCI NIH HHS P01 CA120964NIAMS NIH HHS R01 AR057352NIH HHS 5RO1AR05735210
6 · The paper itself

Abstract

PDGF/VEGF ligands regulate a plethora of biological processes in multicellular organisms via autocrine, paracrine, and endocrine mechanisms. We investigated organ-specific metabolic roles of

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsEgg ProteinsFat BodyHepatocytesMuscle, SkeletalObesitySignal TransductionDrosophila ProteinsEgg ProteinsPvf1 protein, DrosophilaD. melanogastergeneticsgenomicshepatocytemtormyokineobesityPDGFVEGF

Identifiers

PMID33107824
PMCPMC7752135
OpenAlexW3097890604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.