Evidence map›Paper›PMID 33107600›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2021

A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder.

Craig J R Sewall, Jeffrey M Girard, John Merranko, Danella Hafeman, Benjamin I Goldstein, Michael Strober, Heather Hower, Lauren M Weinstock, Shirley Yen, Neal D Ryan and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Craig J R SewallSchool of Social Work, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-1102-5695
Jeffrey M GirardDepartment of Psychology, University of Kansas, Lawrence, KS, USA.
John MerrankoDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Danella HafemanDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Benjamin I GoldsteinDepartment of Psychiatry, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Michael StroberDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Heather HowerDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Lauren M WeinstockDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Shirley YenDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Neal D RyanDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Martin B KellerDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Fangzi LiaoDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Rasim S DilerDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Mary Kay GillDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
David AxelsonDepartment of Psychiatry, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH, USA.
Boris BirmaherDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Tina R GoldsteinDepartment of Psychiatry, Western Psychiatric Hospital, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USBrown University · USNationwide Children's Hospital · USSunnybrook Health Science Centre · CAUniversity of California, Los Angeles · USUniversity of Kansas · US

Funding

Course and Outcome of Bipolar Disorder in Youth - SupplementR01MH059929 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2000 to 2021
$15.9M
Course and Outcome for Bipolar Disorder in Youth (COBY)R01MH059691 · NIMH · BROWN UNIVERSITY · PI KELLER, MARTIN B, YEN, SHIRLEY · 2000 to 2015
$7.9M
Course and Outcome for Bipolar Disorder in YouthR01MH059977 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI STROBER, MICHAEL A · 2000 to 2010
$3.7M
1/2 Predicting Adult Outcomes in Bipolar Youth (PROBY)R01MH112544 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS · 2018 to 2022
$2.5M
NIMH NIH HHS MH59691NIMH NIH HHS MH59929NIMH NIH HHS MH59977NIMH NIH HHS R01 MH112544
6 · The paper itself

Abstract

backgroundYouth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between-person differences - reflecting the average relationship quality across time - and within-person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts.

methodsWe used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex.

resultsPoorer average relationship quality with parents (β = -.33, 95% Bayesian highest density interval (HDI) [-0.54, -0.11]) or friends (β = -.33, 95% HDI [-0.55, -0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (β = -.10, 95% HDI [-0.19, -0.03]) and, to a lesser extent, friends (β = -.06, 95% HDI [-0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (β = -.15, 95% HDI [-0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age.

conclusionsAmong youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time-sensitive indicator of increased risk for SI or suicide attempt.

Indexed as

Bipolar DisorderSuicidal IdeationAdolescentBayes TheoremHumansMultilevel AnalysisRisk FactorsSuicide, AttemptedadolescenceBayesian analysisbipolar disorderparent-child relationshipspeer relationshipsSuicide

Identifiers

PMID33107600
PMCPMC8628509
OpenAlexW3094078427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.