Evidence map›Paper›PMID 33107236›Full record

ArticleYonsei medical journal2020

Survival Effects of Cytoreductive Surgery for Refractory Patients after Neoadjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer.

Wonkyo Shin, Joseph J Noh, Sang Soo Seo, Sokbom Kang, Chel Hun Choi, Sang Yoon Park, Byoung Gie Kim, Myong Cheol Lim

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Wonkyo Shin *Center for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-5728-250X
Joseph J Noh *Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3132-8709
Sang Soo SeoCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0003-2381-0965
Sokbom KangCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-8428-9555
Chel Hun ChoiDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0199-6669
Sang Yoon ParkCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-8325-6009
Byoung Gie KimDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0572-8450
Myong Cheol LimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-8964-7158
National Cancer Center · KRSamsung Medical Center · KRNational Cancer Center · US

Funding

National Cancer Center NCC-1910101-2
6 · The paper itself

Abstract

purposeSalvage second-line chemotherapy is usually recommended for patients with advanced epithelial ovarian cancer (AEOC) who develop progressive disease (PD) after neoadjuvant chemotherapy (NAC). Herein, we investigated the role of cytoreductive surgery (CRS) for such patients. MATERIALS AND

methodsWe retrospectively reviewed the medical records of 36 patients with AEOC who developed PD after receiving NAC at two tertiary academic centers with different treatment strategies between 2001 and 2016. Patients who developed PD after NAC were consistently treated with CRS at one hospital (group A; n=13) and second-line chemotherapy at another (group B; n=23). The clinical characteristics and treatment outcomes were compared between the groups.

resultsOverall survival (OS) was longer in group A than in group B (19.4 months vs. 7.9 months;

conclusionCRS may result in a survival benefit even in patients with AEOC who develop PD after NAC.

Indexed as

AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Ovarian EpithelialCytoreduction Surgical ProceduresDisease-Free SurvivalFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMiddle AgedNeoadjuvant TherapyNeoplasm StagingOvarian NeoplasmsProportional Hazards Modelscytoreductive surgeryepithelial ovarian cancerfollow-up studiesNeoadjuvant therapytreatment outcome

Identifiers

PMID33107236
PMCPMC7593099
OpenAlexW3093711935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.