Evidence map›Paper›PMID 33107141›Full record

ArticleMagnetic resonance in medicine2021

Highly accelerated aortic 4D flow MRI using compressed sensing: Performance at different acceleration factors in patients with aortic disease.

Ashitha Pathrose, Liliana Ma, Haben Berhane, Michael B Scott, Kelvin Chow, Christoph Forman, Ning Jin, Ali Serhal, Ryan Avery, James Carr and 1 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  6. Review
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  9. Comparison of Echo-Planar Imaging and Compressed Sensing in the Estimation of Flow Metrics from Aortic 4D Flow MR Imaging: A Healthy Volunteer Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
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  11. Fully automated on-scanner aortic four-dimensional flow magnetic resonance imaging processing and hemodynamic analysis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  12. Article
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  18. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ashitha PathroseDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0003-1761-0780
Liliana MaDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-8834-8519
Haben BerhaneDepartment of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-1381-7373
Michael B ScottDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-7160-4248
Kelvin ChowDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Christoph FormanSiemens Healthcare, Erlangen, Germany.
Ning JinCardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, Illinois, USA.
Ali SerhalDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Ryan AveryDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-7913-0574
James CarrDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Michael MarklDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Northwestern University · USLurie Children's Hospital · USSiemens Healthcare (United States) · USSiemens Healthineers (Germany) · DE

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Functional Cardiovascular 4D MRI in Congenital Heart DiseaseR01HL115828 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MARKL, MICHAEL, RIGSBY, CYNTHIA K · 2012 to 2021
$5.2M
4D Flow MRI-based assessment of atrial fibrillationF30HL137279 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MA, LILIANA · 2017 to 2020
$189k
Evaluation of Aortic Hemodynamics and Compliance in Aortic StenosisF30HL145995 · NHLBI · NORTHWESTERN UNIVERSITY · PI SCOTT, MICHAEL BARAN · 2019 to 2022
$170k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS F30 HL137279NHLBI NIH HHS F30 HL145995NHLBI NIH HHS R01 HL115828
6 · The paper itself

Abstract

purposeTo systematically assess the feasibility and performance of a highly accelerated compressed sensing (CS) 4D flow MRI framework at three different acceleration factors (R) for the quantification of aortic flow dynamics and wall shear stress (WSS) in patients with aortic disease.

methodsTwenty patients with aortic disease (58 ± 15 y old; 19 M) underwent four 4D flow scans: one conventional (GRAPPA, R = 2) and three CS 4D flows with R = 5.7, 7.7, and 10.2. All scans were acquired with otherwise equivalent imaging parameters on a 1.5T scanner. Peak-systolic velocity (V

resultsMean scan times for the conventional and CS 4D flows with R = 5.7, 7.7, and 10.2 were 9:58 ± 2:58 min, 3:40 ± 1:19 min, 2:50 ± 0:56 min, and 2:05 ± 0:42 min, respectively. V

conclusionsHighly accelerated aortic CS 4D flow at R = 5.7, 7.7, and 10.2 showed moderate agreement with the conventional 4D flow, despite systematically underestimating various hemodynamic parameters. The shortened scan time may enable the clinical translation of CS 4D flow, although potential hemodynamic underestimation should be considered when interpreting the results.

Indexed as

AortaAortic DiseasesAccelerationBlood Flow VelocityHemodynamicsHumansImaging, Three-DimensionalMagnetic Resonance Imaging4D flowaortacardiovascularcompressed sensing

Identifiers

PMID33107141
PMCPMC7846046
OpenAlexW3094493904

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.