ArticleEuropean journal of nuclear medicine and molecular imaging2021
Clinical implications of increased uptake in bone marrow and spleen on FDG-PET in patients with bacteremia.
Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 26 citations in OpenAlex.
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- Neutrophil-to-Lymphocyte Ratio, Bone Marrow, and Visceral Fat Metabolism as Predictors of Future Cardiovascular Disease in an Asymptomatic Healthy Population.Journal of clinical medicine · 2025Article
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- Prospective evaluation of the diagnostic accuracy of FDG-PET/CT for the detection of sternal wound infection post-sternotomy.EJNMMI reports · 2025Article
- Diffuse bone marrow uptake onRadiology case reports · 2024Article
- Baseline [European journal of nuclear medicine and molecular imaging · 2024Article
- Comparison of post-COVID-19 vaccination hypermetabolic lymphadenopathy onEuropean journal of medical research · 2023Article
- Prognostic Value of Bone Marrow Uptake Using 18F-FDG PET/CT Scans in Solid Neoplasms.Journal of imaging · 2022Article
- Evaluation of pediatric malignancies using total-body PET/CT with half-dose [European journal of nuclear medicine and molecular imaging · 2022Article
- Semi-automated histogram analysis of normal bone marrow usingBMC medical imaging · 2022Article
- Abnormality Pattern of F-18 FDG PET Whole Body with Functional MRI Brain in Post-Acute COVID-19.Nuclear medicine and molecular imaging · 2022Article
- Predicting treatment outcomes usingTherapeutic advances in medical oncology · 2022Article
- Long COVID hallmarks on [18F]FDG-PET/CT: a case-control study.European journal of nuclear medicine and molecular imaging · 2021Article
- Immune Response Visualized In Vivo by [18F]-FDG PET/CT after COVID-19 Vaccine.Diagnostics (Basel, Switzerland) · 2021Article
- Development and Validation of a Nomogram Based onFrontiers in medicine · 2021Article
- Utility ofIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate which clinical factors and laboratory values are associated with high FDG uptake in the bone marrow and spleen on 2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) in patients with bacteremia.
methodsOne hundred forty-five consecutive retrospective patients with bacteremia who underwent FDG-PET/CT between 2010 and 2017 were included. Mean standard uptake values (SUV
resultsC-reactive protein (p = 0.006), a cardiovascular or musculoskeletal focus of infection (p = 0.000 for both), and bacteremia caused by Gram-negative bacteria (p = 0.002) were independently and positively associated with BLR, while age (p = 0.000) and glucose level before FDG-PET/CT (p = 0.004) were independently and negatively associated with BLR. For SLR, CRP (p = 0.001) and a cardiovascular focus of infection (p = 0.020) were independently and positively associated with SLR, while age (p = 0.002) and glucose level before FDG-PET/CT (p = 0.016) were independently and negatively associated with SLR.
conclusionHigh FDG uptake in the bone marrow is associated with a higher inflammatory response and younger age in patients with bacteremia. In patients with high FDG uptake in the bone marrow, a cardiovascular or musculoskeletal focus of infection is more likely than other foci, and the infection is more often caused by Gram-negative species. High splenic FDG uptake is associated with a higher inflammatory response as well, and a cardiovascular focus of infection is also more likely in case of high splenic FDG uptake.
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