Evidence map›Paper›PMID 33106847›Full record

ArticleClinical chemistry2020

Quantification of Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor 2 Protein Expression in Bone Biopsies by Targeted Mass Spectrometry without Acid Decalcification.

Regine M Schoenherr, Uliana J Voytovich, Jeffrey R Whiteaker, Vijayakrishna K Gadi, Julie R Gralow, Amanda G Paulovich

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Regine M SchoenherrClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Uliana J VoytovichClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Jeffrey R WhiteakerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Vijayakrishna K GadiClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Julie R GralowClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Amanda G PaulovichClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Fred Hutch Cancer Center · USUniversity of Washington · USUniversity of Illinois Chicago · US

Funding

Proteo-genomic Discovery, Prioritization and Verification of Cancer BiomarkersU24CA160034 · NCI · BROAD INSTITUTE, INC. · PI CARR, STEVEN A, PAULOVICH, AMANDA G · 2011 to 2016
$16.2M
Targeted immunotherapy of breast cancer with central memory T cellsP50CA138293 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PORTER, PEGGY L. · 2010 to 2014
$11.0M
Proteogenomic Studies aimed at understanding ovarian tumor responses to agents targeting the DNA damage response and translating this knowledge into clinical benefitU01CA214114 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BIRRER, MICHAEL, PAULOVICH, AMANDA G · 2017 to 2021
$8.4M
Clinical translation of a NexGen platform for quantifying protein networks in human biospecimensR01CA235575 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI AMANDA G PAULOVICH · 2019 to 2026
$6.0M
A proteomics research specialist in developing targeted mass spectrometry methods for quantifying proteins important in cancerR50CA211499 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Jeff Whiteaker · 2016 to 2026
$2.8M
Advanced development of immuno-MRM technology to analyze archived cancer tissuesR33CA173300 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PAULOVICH, AMANDA G · 2013 to 2015
$1.2M
NCI NIH HHS P50 CA138293NCI NIH HHS R01 CA235575NCI NIH HHS R33 CA173300NCI NIH HHS R50 CA211499NCI NIH HHS U01 CA214114NCI NIH HHS U24 CA160034
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorBiopsy, NeedleBone and BonesBone NeoplasmsBreast NeoplasmsErb-b2 Receptor Tyrosine KinasesHumansMass SpectrometryProof of Concept StudyReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesReceptors, EstrogenReceptors, ProgesteroneBone metastasisBreast cancer biomarkersDecalcificationERHER2Immunopeptide enrichmentMultiple reaction monitoring-mass spectrometryPR

Identifiers

PMID33106847
PMCPMC8536214
OpenAlexW3094352556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.