ArticleNature cell biology2020
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age.
Abstract readComparative Study
In one paragraph
Article in Nature cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
What it found
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Who cites it
102 citing papers in PubMed, 158 citations in OpenAlex.
- Treating age-related loss of muscle mass and function: Where should we be focusing?The Journal of physiology · 2026Review
- The hallmarks of skeletal muscle health.Nature metabolism · 2026Review
- Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging.Science advances · 2026Article
- A Myocyte-Enriched Long Non-Coding RNA NRMLncR Enhances Myogenesis in Mouse.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Modulation of satellite cell function to alleviate age-related sarcopenia: Electrical stimulation & Ca²⁺ signaling combined approach.iScience · 2026Review
- Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis.Nature aging · 2026Article
- Transcriptomic advances in studies of muscle stem cell aging: From bulk to single-cell and beyond.Cell research · 2026Review
- Article
- The future of Forkhead box O transcription factors.The Biochemical journal · 2026Review
- Maternal lipids prime quiescent neural stem cells to reactivate in response to dietary nutrients.bioRxiv : the preprint server for biology · 2026Article
- Intrinsic muscle stem cell dysfunction underlies functional deficits in models of type 1 diabetes.NPJ Regenerative medicine · 2026Article
- AMPKα1 Deficiency in Macrophages Impairs Tendon Regeneration and Tendon Stem Cell Function via TNF-α-FBP2 Signaling.International journal of biological sciences · 2026Article
- The Role of TXNIP in Skeletal Muscle Physiology and Related Diseases: Current Perspectives.Journal of inflammation research · 2026Review
- Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle.Journal of toxicology and environmental health. Part B, Critical reviews · 2026Review
- Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age.Nature metabolism · 2025Article
- Non-canonical roles of Keap1/Nrf2 in regulating quiescence and early activation in adult muscle stem cells.Nature communications · 2025Article
- FoxO1 signaling in B cell malignancies and its therapeutic targeting.FEBS letters · 2025Review
- Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P.EMBO reports · 2025Article
- Stem Cell Aging and Rejuvenation in the Skeletal Muscle System.Rejuvenation research · 2025Review
- Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength.Cell stem cell · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 10 institutions in 5 countries.
Laura García-Prat *Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Eusebio Perdiguero *Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.ORCID http://orcid.org/0000-0003-3529-8989
Sonia Alonso-Martín *Spanish National Center on Cardiovascular Research (CNIC), Madrid, Spain.ORCID http://orcid.org/0000-0002-3254-0365
Stefania Dell'OrsoLaboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH Bethesda, Bethesda, MD, USA.
Srikanth RavichandranLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Stephen R BrooksBiodata Mining and Discovery Section, NIAMS, NIH Bethesda, Bethesda, MD, USA.
Aster H JuanLaboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH Bethesda, Bethesda, MD, USA.
Silvia CampanarioDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.ORCID http://orcid.org/0000-0002-9942-2179
Kan JiangBiodata Mining and Discovery Section, NIAMS, NIH Bethesda, Bethesda, MD, USA.
Xiaotong HongSpanish National Center on Cardiovascular Research (CNIC), Madrid, Spain.
Laura OrtetDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Vanessa Ruiz-BonillaDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Marta FlándezSpanish National Center on Cardiovascular Research (CNIC), Madrid, Spain.
Victoria MoiseevaDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Elena RebolloMolecular Imaging Platform, Molecular Biology Institute of Barcelona (IBMB-CSIC), Barcelona, Spain.
Mercè JardíDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Hong-Wei SunBiodata Mining and Discovery Section, NIAMS, NIH Bethesda, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-9765-6505
Antonio MusaròDAHFMO-Unit of Histology and Medical Embryology, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-2944-9739
Marco SandriDepartment of Biomedical Science, University of Padova, Padova, Italy.
Antonio Del SolLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.ORCID http://orcid.org/0000-0002-9926-617X
Vittorio SartorelliLaboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH Bethesda, Bethesda, MD, USA. sartorev@mail.nih.gov.ORCID http://orcid.org/0000-0002-9284-3675
Pura Muñoz-CánovesDepartment of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain. pura.munoz@upf.edu.ORCID http://orcid.org/0000-0002-7533-9047
Universitat Pompeu Fabra · ESNational Institute of Arthritis and Musculoskeletal and Skin Diseases · USSpanish National Centre for Cardiovascular Research · ESIkerbasque · ESInstitució Catalana de Recerca i Estudis Avançats · ESInstitut de Biologia Molecular de Barcelona · ESIstituto Pasteur · ITUniversity Health Network · CAUniversity of Luxembourg · LUUniversity of Padua · IT
Funding
TGF-BETA FAMILY AND BONE AND CARTILAGE FORMATIONR01AR041126 · NIAMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI DERYNCK, RIK M. · 1993 to 1996
–ROLE OF THE TGF-B FAMILY IN BONE AND CARTILAGE FORMATIONR55AR041126 · NIAMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI DERYNCK, RIK M. · 1992 to 1992
–Abstract
Tissue regeneration declines with ageing but little is known about whether this arises from changes in stem-cell heterogeneity. Here, in homeostatic skeletal muscle, we identify two quiescent stem-cell states distinguished by relative CD34 expression: CD34
Indexed as
Cell ProliferationCell Self RenewalCellular SenescenceRegenerationAge FactorsAnimalsAntigens, CD34CardiotoxinsCell Cycle ProteinsCells, CulturedForkhead Box Protein O1Forkhead Box Protein O3Forkhead Transcription FactorsGene Expression RegulationMaleMice, Inbred C57BLAntigens, CD34CardiotoxinsCell Cycle ProteinsForkhead Box Protein O1Forkhead Box Protein O3Forkhead Transcription FactorsFoxo1 protein, mouseFoxO3 protein, mouseFoxO4 protein, mouseProto-Oncogene Proteins c-akt
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.