ArticleScientific reports2020
A systematic investigation of human DNA preservation in medieval skeletons.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 81 citations in OpenAlex.
- Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Development and Validation of PCR-Based Ancient DNA Analysis for Italian and Western Balkan Archaeological Collections.Balkan journal of medical genetics : BJMG · 2026Article
- Ancient DNA from the Upper Paleolithic mammoth ivory of Hohle Fels, Germany.Scientific reports · 2026Article
- Insights into infectious diseases through ancient pathogen genomics.Nature reviews. Microbiology · 2026Review
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- µCT scanning effects on aDNA and a multi-step workflow for archaeological petrous portions.PloS one · 2026Article
- Forensic skeletal and molecular anthropology face to face: Combining expertise for identification of human remains.Annals of the New York Academy of Sciences · 2025Review
- Review
- The genomic footprints of migration: how ancient DNA reveals our history of mobility.Genome biology · 2025Review
- The outcasts, the sick, and the undead: atypical burials of the late medieval to modern greater Poland.Scientific reports · 2025Article
- Ancient DNA indicates 3,000 years of genetic continuity in the Northern Iranian Plateau, from the Copper Age to the Sassanid Empire.Scientific reports · 2025Article
- A Post-Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA.Molecular ecology resources · 2025Article
- Patellae as a source of DNA in forensic and archaeological analysis.International journal of legal medicine · 2025Article
- Article
- Petrous bones versus tooth cementum for genetic analysis of aged skeletal remains.International journal of legal medicine · 2025Article
- No Bones About It: Sex Is Binary.Archives of sexual behavior · 2024Article
- A fresh perspective on infrared spectroscopy as a prescreening method for molecular and stable isotopes analyses on ancient human bones.Scientific reports · 2024Article
- Article
- Genetic sexing of subadult skeletal remains.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ancient DNA (aDNA) analyses necessitate the destructive sampling of archaeological material. Currently, the cochlea, part of the osseous inner ear located inside the petrous pyramid, is the most sought after skeletal element for molecular analyses of ancient humans as it has been shown to yield high amounts of endogenous DNA. However, destructive sampling of the petrous pyramid may not always be possible, particularly in cases where preservation of skeletal morphology is of top priority. To investigate alternatives, we present a survey of human aDNA preservation for each of ten skeletal elements in a skeletal collection from Medieval Germany. Through comparison of human DNA content and quality we confirm best performance of the petrous pyramid and identify seven additional sampling locations across four skeletal elements that yield adequate aDNA for most applications in human palaeogenetics. Our study provides a better perspective on DNA preservation across the human skeleton and takes a further step toward the more responsible use of ancient materials in human aDNA studies.
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