Evidence map›Paper›PMID 33106515›Full record

ArticleScientific reports2020

A large deletion on CFA28 omitting ACSL5 gene is associated with intestinal lipid malabsorption in the Australian Kelpie dog breed.

Mitchell J O'Brien, Niek J Beijerink, Mandy Sansom, Sarah W Thornton, Tracy Chew, Claire M Wade

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mitchell J O'BrienSchool of Life and Environmental Sciences, Faculty of Science, University of Sydney, Camperdown, NSW, 2006, Australia. Mitchell.obrien@sydney.edu.au.
Niek J BeijerinkSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW, 2006, Australia.
Mandy SansomCallicoma Kelpies, Grafton, NSW, 2460, Australia.
Sarah W ThorntonSydney School of Veterinary Science, Faculty of Science, University of Sydney, Camperdown, NSW, 2006, Australia.
Tracy ChewSydney Informatic Hub, University of Sydney, Camperdown, NSW, 2006, Australia.
Claire M WadeSchool of Life and Environmental Sciences, Faculty of Science, University of Sydney, Camperdown, NSW, 2006, Australia. Claire.Wade@sydney.edu.au.
University of Sydney · AUBroughton Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inborn errors of metabolism are genetic conditions that can disrupt intermediary metabolic pathways and cause defective absorption and metabolism of dietary nutrients. In an Australian Kelpie breeding population, 17 puppies presented with intestinal lipid malabsorption. Juvenile dogs exhibited stunted postnatal growth, steatorrhea, abdominal distension and a wiry coat. Using genome-wide association analysis, an associated locus on CFA28 (P

Indexed as

AnimalsCoenzyme A LigasesDog DiseasesDogsFemaleGene DeletionGenome-Wide Association StudyIntestine, SmallLipid MetabolismMalabsorption SyndromesMaleMetabolism, Inborn ErrorsPedigreePhenotypeCoenzyme A Ligases

Identifiers

PMID33106515
PMCPMC7589484
OpenAlexW3093503463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.