ArticleNature communications2020
Presence of low virulence chytrid fungi could protect European amphibians from more deadly strains.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Using fluorescent in vitro amphibian cell infection models to quantify pathogenicity of Batrachochytrium dendrobatidis.Methods (San Diego, Calif.) · 2026Article
- Glutathione Impacts Both Batrachochytrium dendrobatidis Virulence and Amphibian Cellular Defense in a Chytridiomycosis Model.MicrobiologyOpen · 2026Article
- Glutathione impacts bothbioRxiv : the preprint server for biology · 2026Article
- Monitoring the Prevalence and Distribution of Chytrid Fungus (Ecology and evolution · 2026Article
- Comparative skin microbiome analyses reveal differences between wild populations and captive groups of the Montseny brook newt (ISME communications · 2026Article
- Homology-mediated transformation of frog-killing fungusProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Host and environmental factors drive prevalence of the pathogen Batrachochytrium dendrobatidis in Central African amphibians.Scientific reports · 2025Article
- In Vitro Infection Model Using A6 Cells Sets the Stage for Host-Journal of fungi (Basel, Switzerland) · 2025Article
- High phenotypic diversity correlated with genomic variation across the European Batrachochytrium salamandrivorans epizootic.PLoS pathogens · 2024Article
- Contribution of host species and pathogen clade to snake fungal disease hotspots in Europe.Communications biology · 2024Article
- Genetic transformation of the frog-killing chytrid fungusProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Stable in vitro fluorescence for enhanced live imaging of infection models for Batrachochytrium dendrobatidis.PloS one · 2024Article
- Body size mediates latitudinal population differences in the response to chytrid fungus infection in two amphibians.Oecologia · 2024Article
- AmphibianVirulence · 2023Article
- Lymphocyte Inhibition by the Salamander-Killing Chytrid Fungus, Batrachochytrium salamandrivorans.Infection and immunity · 2022Article
- Variation in the intestinal microbiota at different developmental stages ofEcology and evolution · 2022Article
- Endemic Lineages ofFrontiers in veterinary science · 2022Article
- Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic.Nature communications · 2021Article
- Early-diverging fungal phyla: taxonomy, species concept, ecology, distribution, anthropogenic impact, and novel phylogenetic proposals.Fungal diversity · 2021Review
- Thermal Performance Curves of Multiple Isolates ofFrontiers in veterinary science · 2021Article
Corrections and comments
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Authors and funding
21 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wildlife diseases are contributing to the current Earth's sixth mass extinction; one disease, chytridiomycosis, has caused mass amphibian die-offs. While global spread of a hypervirulent lineage of the fungus Batrachochytrium dendrobatidis (BdGPL) causes unprecedented loss of vertebrate diversity by decimating amphibian populations, its impact on amphibian communities is highly variable across regions. Here, we combine field data with in vitro and in vivo trials that demonstrate the presence of a markedly diverse variety of low virulence isolates of BdGPL in northern European amphibian communities. Pre-exposure to some of these low virulence isolates protects against disease following subsequent exposure to highly virulent BdGPL in midwife toads (Alytes obstetricans) and alters infection dynamics of its sister species B. salamandrivorans in newts (Triturus marmoratus), but not in salamanders (Salamandra salamandra). The key role of pathogen virulence in the complex host-pathogen-environment interaction supports efforts to limit pathogen pollution in a globalized world.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.