Evidence map›Paper›PMID 33106421›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

A far-red cyanobacteriochrome lineage specific for verdins.

Marcus V Moreno, Nathan C Rockwell, Manuel Mora, Andrew J Fisher, J Clark Lagarias

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Genomic analysis highlights a novel class of DPCF-type cyanobacteriochrome.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Article
  4. Discovery and Engineering of Unique Cyanobacteriochrome GAF Domains.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Circular dichroism spectroscopy reveals multiple phytochrome photoproducts in equilibrium.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  6. Article
  7. Article
  8. Cyanobacteriochromes: A Rainbow of Photoreceptors.Annual review of microbiology · 2024
    Review
  9. Review
  10. Article
  11. Elucidating the origins of phycocyanobilin biosynthesis and phycobiliproteins.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Light- and pH-dependent structural changes in cyanobacteriochrome AnPixJg2.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  16. Protein-chromophore interactions controlling photoisomerization in red/green cyanobacteriochromes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Red Light Optogenetics in Neuroscience.Frontiers in cellular neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marcus V MorenoDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.ORCID 0000-0002-2201-8792
Nathan C RockwellDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.ORCID 0000-0002-7748-7019
Manuel MoraDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.ORCID 0000-0002-9851-4741
Andrew J FisherDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.ORCID 0000-0003-3488-6594
J Clark LagariasDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616; jclagarias@ucdavis.edu.ORCID 0000-0002-2093-0403
University of California, Davis · US

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI MALCOLM S. CAPEL · 2018 to 2026
$34.2M
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
MOLECULAR MECHANISMS OF PHYTOCHROME SIGNALINGR01GM068552 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI LAGARIAS, JOHN CLARK · 2003 to 2020
$5.3M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
NCRR NIH HHS S10 RR029205NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM068552NIGMS NIH HHS T32 GM007377
6 · The paper itself

Abstract

Cyanobacteriochromes (CBCRs) are photoswitchable linear tetrapyrrole (bilin)-based light sensors in the phytochrome superfamily with a broad spectral range from the near UV through the far red (330 to 760 nm). The recent discovery of far-red absorbing CBCRs (frCBCRs) has garnered considerable interest from the optogenetic and imaging communities because of the deep penetrance of far-red light into mammalian tissue and the small size of the CBCR protein scaffold. The present studies were undertaken to determine the structural basis for far-red absorption by JSC1_58120g3, a frCBCR from the thermophilic cyanobacterium

Indexed as

Bacterial ProteinsBiliverdineCyanobacteriaLightPhotoreceptor CellsPhotoreceptors, MicrobialPhycobilinsPhycocyaninPhytochromePorphyrinsBacterial ProteinsBiliverdinePhotoreceptors, MicrobialPhycobilinsPhycocyaninphycocyanobilinPhytochromePorphyrinsverdinbilin-protein interactionbiliproteinphotochromismphylogenic analysisspectral tuning

Identifiers

PMID33106421
PMCPMC7668028
OpenAlexW3094353864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.