Evidence map›Paper›PMID 33106417›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells.

Yang Sui, Lei Qi, Jian-Kun Wu, Xue-Ping Wen, Xing-Xing Tang, Zhong-Jun Ma, Xue-Chang Wu, Ke Zhang, Robert J Kokoska, Dao-Qiong Zheng and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. Structural genome variation drives adaptation of the xylose-fermenting yeast Scheffersomyces stipitis to lignocellulosic hydrolysates.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
  3. Detection of "hidden" mitotic crossovers by long-read DNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Comparative functional genomics ofMicrobiology spectrum · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Mutations and mitotic recombination events in nondividing cells.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Mitotic recombination events and single-base mutations induced by ultraviolet light in G1-arrested yeast cells.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yang SuiInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.ORCID 0000-0001-7285-8733
Lei QiInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.
Jian-Kun WuInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.
Xue-Ping WenInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.
Xing-Xing TangInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.
Zhong-Jun MaInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China.
Xue-Chang WuInstitute of Microbiology, College of Life Science, Zhejiang University, 310058 Hangzhou, China.
Ke ZhangInstitute of Microbiology, College of Life Science, Zhejiang University, 310058 Hangzhou, China; zhangke726@zju.edu.cn zhengdaoqiong@zju.edu.cn tom.petes@duke.edu.
Robert J KokoskaPhysical Sciences Directorate, United States Army Research Office, Research Triangle Park, NC 27709.
Dao-Qiong ZhengInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, 316021 Zhoushan, China; zhangke726@zju.edu.cn zhengdaoqiong@zju.edu.cn tom.petes@duke.edu.
Thomas D PetesDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC 27705; zhangke726@zju.edu.cn zhengdaoqiong@zju.edu.cn tom.petes@duke.edu.
Zhejiang Ocean University · CNDuke University · USZhejiang University · CNUnited States Army Research Office · US

Funding

Genetic regulation of genome stability in yeastR35GM118020 · NIGMS · DUKE UNIVERSITY · PI PETES, THOMAS · 2016 to 2025
$7.0M
NIGMS NIH HHS R35 GM118020
6 · The paper itself

Abstract

Genomic alterations including single-base mutations, deletions and duplications, translocations, mitotic recombination events, and chromosome aneuploidy generate genetic diversity. We examined the rates of all of these genetic changes in a diploid strain of

Indexed as

Chromosome MappingChromosomes, FungalDiploidyGene ConversionGene RearrangementLoss of HeterozygosityMutationPhenotypePolymorphism, Single NucleotideSaccharomyces cerevisiaechromosome rearrangementsloss of heterozygositymutationsspontaneous mitotic recombination

Identifiers

PMID33106417
PMCPMC7668089
OpenAlexW3093825731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.