Evidence map›Paper›PMID 33106323›Full record

ArticleLife science alliance2020

David S Guttery, Rajan Pandey, David Jp Ferguson, Richard J Wall, Declan Brady, Dinesh Gupta, Anthony A Holder, Rita Tewari

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Chemical Biology Tools To Investigate Malaria Parasites.Chembiochem : a European journal of chemical biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

David S GutterySchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK dsg6@le.ac.uk.ORCID 0000-0003-0418-580X
Rajan PandeySchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
David Jp FergusonDepartment of Biological and Medical Sciences, Faculty of Health and Life Science, Oxford Brookes University, Oxford, UK.ORCID 0000-0001-5045-819X
Richard J WallSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.ORCID 0000-0003-3487-3187
Declan BradySchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.ORCID 0000-0001-9150-7840
Dinesh GuptaTranslational Bioinformatics Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.ORCID 0000-0002-7548-8835
Anthony A HolderThe Francis Crick Institute, London, UK.ORCID 0000-0002-8490-6058
Rita TewariSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK rita.tewari@nottingham.ac.uk.ORCID 0000-0003-3943-1847
University of Nottingham · GBInternational Centre for Genetic Engineering and Biotechnology · INOxford Brookes University · GBThe Francis Crick Institute · GB

Funding

Medical Research Council G0900109Medical Research Council G0900278Medical Research Council MR/K011782/1Medical Research Council MR/N023048/1Wellcome Trust
6 · The paper itself

Abstract

Cells use fatty acids (FAs) for membrane biosynthesis, energy storage, and the generation of signaling molecules. 3-hydroxyacyl-CoA dehydratase-DEH-is a key component of very long chain fatty acid synthesis. Here, we further characterized in-depth the location and function of DEH, applying in silico analysis, live cell imaging, reverse genetics, and ultrastructure analysis using the mouse malaria model

Indexed as

AnimalsAnophelesCell DivisionCoenzyme A LigasesEndoplasmic ReticulumEnoyl-CoA HydrataseFatty AcidsFemaleLife Cycle StagesLong-Chain-Fatty-Acid-CoA LigaseMalariaMiceMitosisOocystsPlasmodium bergheiProtozoan ProteinsCoenzyme A LigasesEnoyl-CoA HydrataseFatty AcidsLong-Chain-Fatty-Acid-CoA LigaseProtozoan Proteins

Identifiers

PMID33106323
PMCPMC7652392
OpenAlexW3093735264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.