Evidence map›Paper›PMID 33106269›Full record

ArticleAntimicrobial agents and chemotherapy2020

Secretion of and Self-Resistance to the Novel Fibupeptide Antimicrobial Lugdunin by Distinct ABC Transporters in Staphylococcus lugdunensis.

Sophia Krauss, Alexander Zipperer, Sebastian Wirtz, Julian Saur, Martin C Konnerth, Simon Heilbronner, Benjamin O Torres Salazar, Stephanie Grond, Bernhard Krismer, Andreas Peschel

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Interaction BetweenCurrent pharmaceutical biotechnology · 2026
    Review
  3. Article
  4. Study ofInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Towards sustainable antimicrobial therapies forSustainable microbiology · 2024
    Review
  8. Lugdunin production and activity inMicrobiology spectrum · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Two transporters cooperate to secrete amphipathic peptides from the cytoplasmic and membranous milieus.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. The microbiome-shaping roles of bacteriocins.Nature reviews. Microbiology · 2021
    Review
  15. Mutations in a Membrane Permease orAntimicrobial agents and chemotherapy · 2021
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sophia Krauss *Interfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.
Alexander Zipperer *Interfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.
Sebastian WirtzCluster of Excellence: EXC 2124: Controlling Microbes to Fight Infection, Tübingen, Germany.
Julian SaurCluster of Excellence: EXC 2124: Controlling Microbes to Fight Infection, Tübingen, Germany.
Martin C KonnerthCluster of Excellence: EXC 2124: Controlling Microbes to Fight Infection, Tübingen, Germany.
Simon HeilbronnerInterfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.
Benjamin O Torres SalazarInterfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.
Stephanie GrondCluster of Excellence: EXC 2124: Controlling Microbes to Fight Infection, Tübingen, Germany.
Bernhard KrismerInterfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany b.krismer@uni-tuebingen.de.ORCID 0000-0002-9505-8285
Andreas PeschelInterfaculty Institute of Microbiology and Infection Medicine, Infection Biology, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-3209-8626
German Center for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lugdunin is the first reported nonribosomally synthesized antibiotic from human microbiomes. Its production by the commensal

Indexed as

Anti-Infective AgentsStaphylococcal InfectionsStaphylococcus lugdunensisAnti-Bacterial AgentsATP-Binding Cassette TransportersHumansMicrobial Sensitivity TestsPeptides, CyclicStaphylococcus aureusThiazolidinesAnti-Bacterial AgentsAnti-Infective AgentsATP-Binding Cassette TransporterslugduninPeptides, CyclicThiazolidinesABC transportersdrug resistance mechanismsnatural antimicrobial productsStaphylococcus

Identifiers

PMID33106269
PMCPMC7927808
OpenAlexW3094610458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.