Evidence map›Paper›PMID 33106262›Full record

ReviewAntimicrobial agents and chemotherapy2020

FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development.

James M Byrne, Ursula Waack, Edward A Weinstein, Abhay Joshi, Simone M Shurland, Dmitri Iarikov, Jürgen B Bulitta, Binh An Diep, Tina Guina, William W Hope and 9 more

Open access · greenAbstract readReview
In one paragraph

Review in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Development and validation of a rabbit model ofAntimicrobial agents and chemotherapy · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Development and validation of a rabbit model ofFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
  10. Article
  11. Histopathological Analysis ofPolish journal of microbiology · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 2 countries.

James M ByrneOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA James.Byrne@fda.hhs.gov.ORCID 0000-0003-4796-4934
Ursula WaackOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.ORCID 0000-0003-4517-6790
Edward A WeinsteinOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Abhay JoshiOffice of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.ORCID 0000-0002-8721-6503
Simone M ShurlandOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Dmitri IarikovOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Jürgen B BulittaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.ORCID 0000-0001-7352-3097
Binh An DiepDivision of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Tina GuinaBiomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, Department of Health and Human Services, Washington, DC, USA.
William W HopeDepartment of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-6187-878X
Matthew B LawrenzCenter for Predictive Medicine for Biodefense and Emerging Infectious Diseases, Department of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA.ORCID 0000-0003-1505-5429
Alexander J LepakDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Brian M LunaDepartment of Molecular Microbiology and Immunology, Keck School of Medicine of USC, Los Angeles, California, USA.ORCID 0000-0001-6718-4551
Lynn MieselPharmacology Discovery Services, Ltd., New Taipei City, Taiwan.
Andrew J PhippsTunnell Government Services, Biomedical Advanced Research and Development Authority, Washington, DC, USA.
Thomas J WalshTransplantation-Oncology Infectious Diseases Program, Departments of Medicine, Pediatrics, and Microbiology & Immunology, Weill Cornell Medicine of Cornell University, New York, New York, USA.
William WeissPreClinical Services, UNT System College of Pharmacy, Fort Worth, Texas, USA.
Thushi AminiOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
John J FarleyOffice of Infectious Diseases, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
United States Food and Drug Administration · USBiomedical Advanced Research and Development Authority · USOak Ridge Associated Universities · USCornell University · USKeck Hospital of USC · USUniversity of California, San Francisco · USUniversity of Florida · USUniversity of Liverpool · GBUniversity of Louisville · USUniversity of North Texas System · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The U.S. Food and Drug Administration (FDA) hosted a public workshop entitled "Advancing Animal Models for Antibacterial Drug Development" on 5 March 2020. The workshop mainly focused on models of pneumonia caused by

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsAnimalsDrug DevelopmentMiceModels, AnimalRabbitsSwineUnited StatesUnited States Food and Drug AdministrationAnti-Bacterial Agentsanimal modelsantibacterialantibioticsdrug developmentFDAhumanized dosepneumoniaregulatoryworkshop

Identifiers

PMID33106262
PMCPMC7927847
OpenAlexW3093543675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.