Evidence map›Paper›PMID 33106261›Full record

ArticleAntimicrobial agents and chemotherapy2020

Patients with Erythema Migrans: Characterizing the Impact of Initiation of Antibiotic Therapy Prior to Study Enrollment.

Gary P Wormser, Donna McKenna, Eliana Jacobson, Elayna M Shanker, Keith D Shaffer, Carol Scavarda, Paul Visintainer

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gary P WormserDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA gwormser@nymc.edu.ORCID 0000-0002-8743-0948
Donna McKennaDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA.
Eliana JacobsonDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA.
Elayna M ShankerDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA.
Keith D ShafferDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA.
Carol ScavardaDivision of Infectious Diseases, New York Medical College, Valhalla, New York, USA.
Paul VisintainerBaystate Medical Center, Springfield, Massachusetts, USA.
New York Medical College · USBaystate Medical Center · US

Funding

NCEZID CDC HHS R01 CK000152
6 · The paper itself

Abstract

Erythema migrans is the most common clinical manifestation of Lyme disease, with concomitant subjective symptoms occurring in ∼65% of cases in the United States. We evaluated the impact of having been started on antibiotic treatment before study enrollment on 12 particular symptoms for 38 subjects with erythema migrans versus 52 untreated subjects. There were no significant differences in the frequency of having at least one symptom or in the symptom severity score on study entry. However, the frequency of having at least one symptom was significantly greater for those who had received <7 days of antibiotic treatment than for those who had been treated for ≥7 days (23/24 [95.8%] versus 8/14 [57.1%],

Indexed as

Erythema Chronicum MigransLyme DiseaseAnti-Bacterial AgentsErythemaFemaleHumansMaleAnti-Bacterial AgentsantibioticsBorrelia burgdorferierythema migransLyme diseasesymptoms

Identifiers

PMID33106261
PMCPMC7927866
OpenAlexW3094516446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.