ArticleAntimicrobial resistance and infection control2020
Antibiotic appropriateness and adherence to local guidelines in perioperative prophylaxis: results from an antimicrobial stewardship intervention.
Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Appropriateness of surgical antibiotic prophylaxis in Spanish hospitals: a national multicentre cross-sectional study.The Lancet regional health. Europe · 2026Article
- The Development and Implementation of New Recommendations for Perioperative Antibiotic Prophylaxis Duration in Elective Primary Hip and Knee Replacement Surgeries.Journal of clinical medicine · 2026Article
- Adherence to perioperative antimicrobial prophylaxis in cancer surgeries: A single-center retrospective study from Oman.IJID regions · 2026Article
- Extended antibiotic prophylaxis beyond 24 h after pancreatic surgery: prevalence and risk factors.Frontiers in public health · 2026Article
- Article
- Rates of post procedural prophylactic antibiotic use following cardiac implantable electronic device insertion and the impact on surgical site infections in Alberta, Canada.Antimicrobial resistance and infection control · 2024Article
- Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey.JAC-antimicrobial resistance · 2024Article
- Surgical Antibiotic Prophylaxis Administration Improved after introducing Dedicated Guidelines: A Before-and-After Study from Dhulikhel Hospital in Nepal (2019-2023).Tropical medicine and infectious disease · 2023Article
- Article
- Point prevalence survey of antibiotic use among hospitalized patients across 41 hospitals in Thailand.JAC-antimicrobial resistance · 2023Article
- ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023Article
- Perioperative Antibiotic Prophylaxis in Pediatric Cardiac Surgery-Simple Is Better.Antibiotics (Basel, Switzerland) · 2022Article
- Impact of collaborative physician-pharmacist stewardship strategies on prophylactic antibiotic practices: a quasi-experimental study.Antimicrobial resistance and infection control · 2022Observational
- Trends in guideline implementation: an updated scoping review.Implementation science : IS · 2022Article
- Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh.Antibiotics (Basel, Switzerland) · 2022Article
- Implementing an Antimicrobial Stewardship Programme to Improve Adherence to a Perioperative Prophylaxis Guideline.Healthcare (Basel, Switzerland) · 2022Article
- Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital.Frontiers in pharmacology · 2022Article
- Postoperative complications: an observational study of trends in the United States from 2012 to 2018.BMC surgery · 2021Observational
- Point Prevalence Survey of Antimicrobial Use in Four Tertiary Care Hospitals in Mexico.Infection and drug resistance · 2021Article
- Perioperative antibiotic prophylaxis in spinal surgery.SICOT-J · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSurgical antibiotic prophylaxis (SAP) represents a major indication of antibiotic consumption worldwide. The present study aims to report the results of an enabling, long-term AMS intervention conducted between 2013 and 2019 on an Italian University Hospital performing more than 40.000 surgical interventions per year.
methodsSAP inappropriateness was defined according to the ASHP guidelines and divided in four main categories: indication, selection and dosing, duration, timing. Between 2013 and 2019, we conducted a continuative AMS intervention over 14 surgical departments that included enablement, review of selected clinical records and feedback.
resultsWe collected a total of 789 SAP prescribed to 735 patients (mean age 56.7 ± 17.8y). Overall, guideline adherence improved from 36.6% (n = 149) at baseline to 57.9% (n = 221) post-intervention (P < 0.0001). A significant improvement (P < 0.001) was also detected for each category: indication (from 58.5 to 93.2%), selection and dosing (from 58.5 to 80.6%), timing (from 92.4 to 97.6%), duration (from 71 to 80.1%).
conclusionsThough results cannot be generalized to all hospital populations, enabling AMS interventions may be effective in establishing a sustained improvement in SAP appropriateness rates. Once identified the main causes of SAP inappropriateness, tailored AMS interventions for each department may be beneficial. Further studies are needed to evaluate specific outcomes as incidence of surgical site infections and antimicrobial resistance.
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