Evidence map›Paper›PMID 33105888›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Super-Resolution Imaging with Ultrasound for Visualization of the Renal Microvasculature in Rats Before and After Renal Ischemia: A Pilot Study.

Sofie Bech Andersen, Iman Taghavi, Carlos Armando Villagómez Hoyos, Stinne Byrholdt Søgaard, Fredrik Gran, Lars Lönn, Kristoffer Lindskov Hansen, Jørgen Arendt Jensen, Michael Bachmann Nielsen, Charlotte Mehlin Sørensen

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05754814 (SUper-Resolution Ultrasound Imaging of Erythrocytes), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05754814 completednot on this mapstarted 2022, after this paper: background citation

SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes

TypeobservationalSponsorRigshospitalet, DenmarkRan2022 to 2026Enrolled20ConditionsHead and Neck Cancer, Lymphoma, Lymph Node MetastasisArmsMalignant lymph nodes
3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. OptimizingPhysics in medicine and biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Acceleration-Based Kalman Tracking for Super-Resolution Ultrasound Imaging In Vivo.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  17. Review
  18. Article
  19. Assessments of microvascular function in organ systems.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofie Bech AndersenDepartment of Radiology, Rigshospitalet, 2100 Copenhagen, Denmark.
Iman TaghaviCenter for Fast Ultrasound Imaging, Department of Health Technology, Technical University of Denmark, 2800 Lyngby, Denmark.ORCID 0000-0002-2551-074X
Carlos Armando Villagómez HoyosBK Medical ApS, 2730 Herlev, Denmark.
Stinne Byrholdt SøgaardDepartment of Radiology, Rigshospitalet, 2100 Copenhagen, Denmark.
Fredrik GranBK Medical ApS, 2730 Herlev, Denmark.
Lars LönnDepartment of Radiology, Rigshospitalet, 2100 Copenhagen, Denmark.
Kristoffer Lindskov HansenDepartment of Radiology, Rigshospitalet, 2100 Copenhagen, Denmark.
Jørgen Arendt JensenCenter for Fast Ultrasound Imaging, Department of Health Technology, Technical University of Denmark, 2800 Lyngby, Denmark.
Michael Bachmann NielsenDepartment of Radiology, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-9380-1688
Charlotte Mehlin SørensenDepartment of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.

Funding

Innovationsfonden 7050-00004B
6 · The paper itself

Abstract

In vivo monitoring of the microvasculature is relevant since diseases such as diabetes, ischemia, or cancer cause microvascular impairment. Super-resolution ultrasound imaging allows in vivo examination of the microvasculature by detecting and tracking sparsely distributed intravascular microbubbles over a minute-long period. The ability to create detailed images of the renal vasculature of Sprague-Dawley rats using a modified clinical ultrasound platform was investigated in this study. Additionally, we hypothesized that early ischemic damage to the renal microcirculation could be visualized. After a baseline scan of the exposed kidney, 10 rats underwent clamping of the renal vein (

Indexed as

kidneymicrocirculationratsreperfusion injurySprague-Dawleysuper-resolution ultrasound imagingvasa recta

Identifiers

PMID33105888
PMCPMC7690607

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.