ArticleMolecules (Basel, Switzerland)2020
Target and Suspect HRMS Metabolomics for the Determination of Functional Ingredients in 13 Varieties of Olive Leaves and Drupes from Greece.
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed.
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- Elucidating the (lipo)Phenolic Composition of Olive Oil By-Products and Biomass From Three Different Olea Europaea Cultivars by Liquid Chromatography Coupled to Photodiode Array and Mass Spectrometry.Journal of separation science · 2025Article
- A Novel Liquid Chromatographic Time-of-Flight Tandem Mass Spectrometric Method for the Determination of Secondary Metabolites in Functional Flours Produced from Grape Seed and Olive Stone Waste.Molecules (Basel, Switzerland) · 2025Article
- Effects ofIranian journal of basic medical sciences · 2024Article
- Comparative Analysis of Chemical Composition ofMolecules (Basel, Switzerland) · 2023Article
- Metabolomics Approach to Characterize Green Olive Leaf Extracts Classified Based on Variety and Season.Plants (Basel, Switzerland) · 2022Article
- Impact of Geraniol and Geraniol Nanoemulsions onPlants (Basel, Switzerland) · 2022Article
- Fruit Phenolic and Triterpenic Composition of Progenies ofPlants (Basel, Switzerland) · 2022Article
- A Validated Ultrasound-Assisted Extraction Coupled with SPE-HPLC-DAD for the Determination of Flavonoids in By-Products of Plant Origin: An Application Study for the Valorization of the Walnut Septum Membrane.Molecules (Basel, Switzerland) · 2021Article
- Characterization of the Phenolic Fingerprint ofMolecules (Basel, Switzerland) · 2021Article
- HPLC Fingerprints for the Characterization of Walnuts and the Detection of Fraudulent Incidents.Foods (Basel, Switzerland) · 2021Article
- A Rapid HPLC-UV Protocol Coupled to Chemometric Analysis for the Determination of the Major Phenolic Constituents and Tocopherol Content in Almonds and the Discrimination of the Geographical Origin.Molecules (Basel, Switzerland) · 2021Article
- Geographical Characterization of Olive Oils from the North Aegean Region Based on the Analysis of Biophenols with UHPLC-QTOF-MS.Foods (Basel, Switzerland) · 2021Article
- Biophenolic Profile Modulations in Olive Tissues as Affected by Manganese Nutrition.Plants (Basel, Switzerland) · 2021Article
- Bioactive Compounds in Waste By-Products from Olive Oil Production: Applications and Structural Characterization by Mass Spectrometry Techniques.Foods (Basel, Switzerland) · 2021Review
- Rare Earths as Authenticity Markers for the Discrimination of Greek and Turkish Pistachios Using Elemental Metabolomics and Chemometrics.Foods (Basel, Switzerland) · 2021Article
- HPLC-HRMS Global Metabolomics Approach for the Diagnosis of "Olive Quick Decline Syndrome" Markers in Olive Trees Leaves.Metabolites · 2021Article
- Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations.International journal of biological sciences · 2021Review
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4 authors.
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Abstract
The huge interest in the health-related properties of foods to improve health has brought about the development of sensitive analytical methods for the characterization of natural products with functional ingredients. Greek olive leaves and drupes constitute a valuable source of biophenols with functional properties. A novel ultra-high-performance liquid chromatography-quadrupole time of flight tandem mass spectrometry (UHPLC-QTOF-MS) analytical method was developed to identify biophenols through target and suspect screening in Greek olive leaves and drupes of the varieties: Koroneiki, Throumbolia, Konservolia, Koutsourelia, Kalamon, Petrolia, Amigdalolia, Megaritiki, Mastoeidis, Agouromanakolia, Agrilia, Adramitiani and Kolovi. The method's performance was evaluated using the target compounds: oleuropein, tyrosol and hydroxytyrosol. The analytes demonstrated satisfactory recovery efficiency for both leaves (85.9-90.5%) and drupes (89.7-92.5%). Limits of detection (LODs) were relatively low over the range 0.038 (oleuropein)-0.046 (hydroxytyrosol) and 0.037 (oleuropein)-0.048 (hydroxytyrosol) for leaves and drupes, respectively For leaves, the precision limit ranged between 4.7 and 5.8% for intra-day and between 5.8 and 6.5% for inter-day experiments, and for drupes, it ranged between 3.8 and 5.2% for intra-day and between 5.1 and 6.2% for inter-day experiments, establishing the good precision of the method. The regression coefficient (r
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