Evidence map›Paper›PMID 33105724›Full record

ReviewPlants (Basel, Switzerland)2020

Jiri Patocka, Kanchan Bhardwaj, Blanka Klimova, Eugenie Nepovimova, Qinghua Wu, Marco Landi, Kamil Kuca, Martin Valis, Wenda Wu

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Validation of a Traditional Medicine,Pharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiri PatockaBiomedical Research Centre, University Hospital, 50003 Hradec Kralove, Czech Republic.ORCID 0000-0002-1261-9703
Kanchan BhardwajDepartment of Botany, Shoolini University of Biotechnology and Management Sciences, Solan 173229, H.P., India.
Blanka KlimovaDepartment of Neurology of the Medical Faculty of Charles University and University Hospital in Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic.ORCID 0000-0001-8000-9766
Eugenie NepovimovaDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Qinghua WuDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Marco LandiDepartment of Agriculture, Food and Environment, University of Pisa, Via del Borghetto Pisa 80, 56124 Pisa, Italy.ORCID 0000-0003-0121-0715
Kamil KucaBiomedical Research Centre, University Hospital, 50003 Hradec Kralove, Czech Republic.ORCID 0000-0001-9664-1109
Martin ValisDepartment of Neurology of the Medical Faculty of Charles University and University Hospital in Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic.
Wenda WuDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.ORCID 0000-0003-2528-4655

Funding

UHK EXCELLENCE
6 · The paper itself

Abstract

Fruit-derived bioactive substances have been spotlighted as a regulator against various diseases due to their fewer side effects compared to chemical drugs. Among the most frequently consumed fruits, apple is a rich source of nutritional molecules and contains high levels of bioactive compounds. The main structural classes of apple constituents include polyphenols, polysaccharides (pectin), phytosterols, and pentacyclic triterpenes. Also, vitamins and trace elements complete the nutritional features of apple fruit. There is now considerable scientific evidence that these bioactive substances present in apple and peel have the potential to improve human health, for example contributing to preventing cardiovascular disease, diabetes, inflammation, and cancer. This review will focus on the current knowledge of bioactive substances in apple and their medicinal value for human health.

Indexed as

applebioactive compoundshuman healthphytosterolpolyphenolpolysaccharidetriterpene

Identifiers

PMID33105724
PMCPMC7690411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.