Evidence map›Paper›PMID 33105655›Full record

ArticleMolecules (Basel, Switzerland)2020

Enhancement of Phthalocyanine Mediated Photodynamic Therapy by Catechin on Lung Cancer Cells.

Giftson J Senapathy, Blassan P George, Heidi Abrahamse

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Therapeutic Efficacy ofPlants (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Giftson J SenapathyLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, 2028 Doornfontein, South Africa.
Blassan P GeorgeLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, 2028 Doornfontein, South Africa.
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, 2028 Doornfontein, South Africa.ORCID 0000-0001-5002-827X
University of Johannesburg · ZA

Funding

South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa 98337
6 · The paper itself

Abstract

Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers, is an advanced treatment method with relatively few side effects. Plant products are emerging as potent photosensitizers (PSs). The dose-dependent effect of Catechin (CA) (20-100 µM) on cellular morphological changes, cell viability, cytotoxicity, proliferation, DNA damage and apoptosis were studied on A549 adenocarcinoma alveolar basal epithelial cells. The effect of CA, along with Zinc phthalocyanine PS at 680 nm and 5 J/cm

Indexed as

A549 CellsAntineoplastic AgentsApoptosisCatechinCell ProliferationDNA DamageDose-Response Relationship, DrugDrug SynergismHumansIndolesIsoindolesLung NeoplasmsOrganometallic CompoundsPhotochemotherapyPhotosensitizing AgentsReactive Oxygen SpeciesAntineoplastic AgentsCatechinIndolesIsoindolesOrganometallic CompoundsPhotosensitizing AgentsReactive Oxygen SpeciesZinc CompoundsZn(II)-phthalocyaninecancer treatmentcatechindose-responselung cancernatural productphotodynamic therapyphytochemical

Identifiers

PMID33105655
PMCPMC7659931
OpenAlexW3093886366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.