Evidence map›Paper›PMID 33105628›Full record

ArticleMicroorganisms2020

A Multi-Omic Analysis for Low Bone Mineral Density in Postmenopausal Women Suggests a RELATIONSHIP between Diet, Metabolites, and Microbiota.

Berenice Palacios-González, Eric G Ramírez-Salazar, Berenice Rivera-Paredez, Manuel Quiterio, Yvonne N Flores, Luis Macias-Kauffer, Sofía Moran-Ramos, Edgar Denova-Gutiérrez, Isabel Ibarra-González, Marcela Vela-Amieva and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Gut microbiome and bone health: update on mechanisms, clinical correlations, and possible treatment strategies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Links between bone fractures and the gut microbiota.Nature reviews. Endocrinology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Berenice Palacios-GonzálezUnidad de Vinculación Científica, Facultad de Medicina, UNAM-INMEGEN, Ciudad de México 04510, Mexico.
Eric G Ramírez-SalazarConsejo Nacional de Ciencia y Tecnología (CONACYT)-Laboratorio de Genómica del Metabolismo Óseo, Instituto Nacional de Medicina Genómica (INMEGEN), Ciudad de Mexico 14610, Mexico.ORCID 0000-0002-0767-9357
Berenice Rivera-ParedezCentro de Investigación en Políticas, Población y Salud de la Facultad de Medicina, UNAM, Ciudad de México 04510, Mexico.
Manuel QuiterioCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos 62100, Mexico.
Yvonne N FloresUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social (IMSS), Cuernavaca, Morelos 62000, Mexico.ORCID 0000-0002-0601-357X
Luis Macias-KaufferUnidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/Instituto Nacional de Medicina Genómica (INMEGEN), Ciudad de México 14610, Mexico.ORCID 0000-0002-3080-2835
Sofía Moran-RamosConsejo Nacional de Ciencia y Tecnología (CONACYT)- Unidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/Instituto Nacional de Medicina Genómica (INMEGEN), Ciudad de México 14610, Mexico.
Edgar Denova-GutiérrezCentro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública, Cuernavaca, Morelos 62100, Mexico.
Isabel Ibarra-GonzálezUnidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas, UNAM, Ciudad de México 04530, Mexico.
Marcela Vela-AmievaLaboratorio de Errores Innatos del Metabolismo y Tamiz, Instituto Nacional de Pediatría, Ciudad de México 04530, Mexico.
Samuel Canizales-QuinterosUnidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/Instituto Nacional de Medicina Genómica (INMEGEN), Ciudad de México 14610, Mexico.
Jorge SalmerónCentro de Investigación en Políticas, Población y Salud de la Facultad de Medicina, UNAM, Ciudad de México 04510, Mexico.
Rafael Velázquez-CruzLaboratorio de Genómica del Metabolismo Óseo, Instituto Nacional de Medicina Genómica (INMEGEN), Ciudad de México 14610, Mexico.ORCID 0000-0003-4515-0777
National Institute of Genomic Medicine · MXInstituto Nacional de Salud Pública · MXInstituto Nacional de Pediatria · MXKaiser Permanente · US

Funding

Genetic and Environmental Risk of Liver Disease/Cancer among MexicansK07CA197179 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FLORES, YVONNE NICOLE · 2015 to 2019
$805k
Instituto Nacional de Medicina Genómica 346-05/2018/IInstituto Nacional de Medicina Genómica 399-07/2019/INCI NIH HHS K07 CA197179
6 · The paper itself

Abstract

The effect of microbiota composition and its health on bone tissue is a novel field for research. However, their associations with bone mineral density (BMD) have not been established in postmenopausal women. The present study investigates the relation of diet, the microbiota composition, and the serum metabolic profile in postmenopausal women with normal-BMD or with low-BMD. Ninety-two Mexican postmenopausal women were classified into normal-BMD (

Indexed as

bone healthbone mineral densityestrogen deficiencyinflammationintestinal microbiotalycopenepostmenopausal womenvitamin D deficiency

Identifiers

PMID33105628
PMCPMC7690388
OpenAlexW3093849869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.