Evidence map›Paper›PMID 33105582›Full record

ArticleBiology2020

The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial.

Hendrika W Grievink, Pim Gal, Maria Ozsvar Kozma, Erica S Klaassen, Johan Kuiper, Jacobus Burggraaf, Christoph J Binder, Matthijs Moerland

Open access · goldAbstract read
In one paragraph

Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Mitigating atherosclerosis: Integrating vaccines with gene targets.American heart journal plus : cardiology research and practice · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hendrika W GrievinkCentre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-5611-108X
Pim GalCentre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Maria Ozsvar KozmaDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Erica S KlaassenCentre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Johan KuiperDivision of BioTherapeutics, Leiden Academic Center for Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.
Jacobus BurggraafCentre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.ORCID 0000-0001-7912-0918
Christoph J BinderDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-8313-7050
Matthijs MoerlandCentre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Leiden University Medical Center · NLLeiden University · NLMedical University of Vienna · ATCentre for Human Drug Research · NL

Funding

European Union, call FP7-HEALTH-2013-INNOVATION project ID 603131
6 · The paper itself

Abstract

In mice vaccination with

Indexed as

atherosclerosiscardiovascular diseaseclinical trialsoxLDLphosphorylcholinetranslational medicinevaccine

Identifiers

PMID33105582
PMCPMC7716233
OpenAlexW3094063848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.