Evidence map›Paper›PMID 33105563›Full record

ArticleInternational journal of molecular sciences2020

In the Model Host

Kiho Lee, Iliana Escobar, Yeeun Jang, Wooseong Kim, Frederick M Ausubel, Eleftherios Mylonakis

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Microbial genomics · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Innate immunity in C. elegans.Current topics in developmental biology · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kiho LeeDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Iliana EscobarDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Yeeun JangDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Wooseong KimCollege of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.
Frederick M AusubelDepartment of Genetics, Harvard Medical School and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-6927-8460
Eleftherios MylonakisDivision of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Brown University · USEwha Womans University · KRHarvard University · US

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI David C Hooper · 2009 to 2026
$39.4M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
National Institute of Allergy and Infectious Diseases P01AI083214NIDDK NIH HHS P30 DK040561NIH HHS P40 OD010440
6 · The paper itself

Abstract

Sphingosine-1-phophate (S1P) is a sphingolipid-derived signaling molecule that controls diverse cellular functions including cell growth, homeostasis, and stress responses. In a variety of metazoans, cytosolic S1P is transported into the extracellular space where it activates S1P receptors in a concentration-dependent manner. In the free-living nematode

Indexed as

AnimalsAnti-Bacterial AgentsBasic Helix-Loop-Helix ProteinsCaenorhabditis elegansCaenorhabditis elegans ProteinsEscherichia coliHost-Pathogen InteractionsHumansLongevityLysophospholipidsMembrane ProteinsMutationp38 Mitogen-Activated Protein KinasesPhosphotransferases (Alcohol Group Acceptor)Pseudomonas aeruginosaSignal TransductionAnti-Bacterial AgentsBasic Helix-Loop-Helix ProteinsCaenorhabditis elegans ProteinsHLH-30 protein, C elegansLysophospholipidsMembrane Proteinsp38 Mitogen-Activated Protein KinasesPhosphotransferases (Alcohol Group Acceptor)Sphingosinesphingosine 1-phosphateSphingosine Kinasespin-1 protein, C elegansCaenorhabditis elegansimmunityKeywords: Sphingosine-1-phosphatepathogenic bacteriaS1PS1P kinaseS1P transporters

Identifiers

PMID33105563
PMCPMC7672543
OpenAlexW3093830959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.