Evidence map›Paper›PMID 33104914›Full record

ArticleSurgical endoscopy2021

The POEM bottom-up technique for achalasia.

Gad Marom, Harold Jacob, Ariel Benson, Tiberiu Hershcovici, Rachel Gefen, Jonathan B Yuval, Ronit Brodie, Avraham I Rivkind, Yoav Mintz

Abstract read
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Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Post-POEM Contrast-Enhanced Swallow Study: Is It Always Necessary?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gad MaromDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Harold JacobDepartment of Gastroenterology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Ariel BensonDepartment of Gastroenterology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Tiberiu HershcoviciDepartment of Gastroenterology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Rachel GefenDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Jonathan B YuvalDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Ronit BrodieDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Avraham I RivkindDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Yoav MintzDepartment of General Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. ymintz@hadassah.org.il.ORCID 0000-0002-5101-7449
Hadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPOEM (Per Oral Endoscopic Myotomy) is rapidly becoming a valid option for surgical myotomy in achalasia patients. Several techniques to perform POEM are described, but all concentrate on the division of the circular muscle fibers in a proximal-to-distal fashion. Our aim is to present the distal-to-proximal, or the bottom-up technique using the Flush/Dual knife, which overcomes the disadvantages of the standard technique.

methodsA retrospective study on a prospectively maintained database was performed on all patients treated by POEM in our institution. Clinical presentation, operating time, adverse events, and outcomes were studied.

resultsPOEM was performed on 105 achalasia patients. The first 15 cases were performed using the standard technique and were compared to the next 90 cases performed using the bottom-up technique. The average preop Eckardt scores in the standard and bottom-up groups were 9.5 and 8.8, respectively, declining to 1.4 and 0.5, 3 months post myotomy (p < 0.001). The average procedure time was 111.2 min for the standard technique and 74.3 for the bottom-up technique. (p = 0.002). Perioperative adverse events included 14 instances of pneumoperitoneum, 3 tunnel leaks, and 4 patients with fever on postoperative day one. Pneumoperitoneum needing decompression and postoperative fever were more prevalent in the standard technique group.

conclusionsAs POEM is becoming more common for the treatment of achalasia, refinements of the technique and instruments used are valuable. We compared our experience of the standard technique to our bottom-up technique and found the latter to be equally effective as well as safer, faster, and easier. We, therefore, suggest considering performing POEM in this technique.

Indexed as

Esophageal AchalasiaNatural Orifice Endoscopic SurgeryEsophageal Sphincter, LowerHumansRetrospective StudiesTreatment OutcomeAchalasiaEckardt scoreNOTES (natural orifice transluminal endoscopic surgery)POEM (peroral endoscopic myotomy)

Identifiers

PMID33104914
OpenAlexW3094326539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.