ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021
Effect of compression fracture on trabecular bone score at lumbar spine.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 27 citations in OpenAlex.
- Development and validation of a clinical risk stratification model for lumbar vertebral compression fractures in patients with lumbar disc herniation.Bone reports · 2026Article
- FRAX score predicts vertebral compression fractures impairing spinal alignment and hip function after total hip arthroplasty: a retrospective cohort study.Arthroplasty (London, England) · 2025Article
- TBS as a complementary tool for assessing vertebral fractures and spinal deformity in children and adolescents with osteogenesis imperfecta.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Vertebral body density role in determining vertebral osteoporotic fracture type and its progression.Clinical anatomy (New York, N.Y.) · 2025Article
- Effect of excluding fractured or abnormal vertebrae on the trabecular bone score measurement.Archives of osteoporosis · 2024Article
- Trabecular bone score as an assessment tool to identify the risk of vertebral fractures in SAPHO syndrome.Archives of osteoporosis · 2024Article
- Best Bisphosphonate Threshold for 10-Year Vertebral and Non-vertebral Fracture Mitigation.Cureus · 2024Article
- Update on trabecular bone score.Archives of endocrinology and metabolism · 2022Review
- Usefulness of the Trabecular Bone Score in Assessing the Risk of Vertebral Fractures in Patients with Cirrhosis.Journal of clinical medicine · 2022Article
- Abnormal Trabecular Bone Score, Lower Bone Mineral Density and Lean Mass in Young Women With Premature Ovarian Insufficiency Are Prevented by Oestrogen Replacement.Frontiers in endocrinology · 2022Article
- Association of short sleep duration and trabecular bone score.Scientific reports · 2021Article
- Analysis of Influencing Factors of Medication Compliance in Patients with Recurrent Vertebral Fractures after Percutaneous Kyphoplasty and the Role of Family-Centered Education Intervention.Evidence-based complementary and alternative medicine : eCAM · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Bone mineral density (BMD) may be increased due to vertebral compression fractures (VCF). Our study showed trabecular bone scores (TBS) was less affected than BMD by fractured vertebrae. The TBS of most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity, could still be used in predicting fracture risk.
introductionTrabecular bone score (TBS), a noninvasive tool estimating bone microarchitecture, provides complementary information to lumbar spine bone mineral density (BMD). Lumbar spine BMD might be increased due to both degenerative disease and vertebral compression fractures (VCF). Lumbar spine TBS has been confirmed not influenced by osteoarthrosis, but the effects of VCF are still not been well evaluated. This study aimed to investigate whether lumbar spine TBS was affected by fractured vertebrae.
methodsWe studied postmenopausal women and men above 50 years old who underwent DXA between January 1, 2017, and May 31, 2019. By calculating the difference of BMD and TBS between L1 and the mean of L2-3, the study compared the difference of values between the control group and fracture group to determine the effects of fractured vertebrae on BMD and TBS.
resultsA total of 377 participants were enrolled with 202 in the control group (157 females; age: 68.06 ± 6.47 years) and 175 in the fracture group (147 females; age: 71.71 ± 9.44 years). The mean BMD of the L1 vertebrae in the fracture group was significantly higher than that in the control group (p < 0.0001). There was no significant difference between the mean differences of TBS between L1 and the means of L2-3 vertebrae in the control group and the most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity.
conclusionLumbar spine TBS, unlike BMD, is less affected by fractured vertebrae. The TBS of most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity, could still be used in predicting fracture risk.
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