ArticlePLoS neglected tropical diseases2020
Spatiotemporal transmission dynamics of co-circulating dengue, Zika, and chikungunya viruses in Fortaleza, Brazil: 2011-2017.
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- A descriptive assessment of mitochondrial COI genetic diversity and dengue and chikungunya RNA detection in Aedes aegypti across eight provinces in Thailand.Parasites & vectors · 2026Article
- [Spread and persistence of chikungunya in the Brazilian Northeast (2015-2023): A spatiotemporal analysisAnálisis espaciotemporal de la expansión y la persistencia del chikunguña en el noreste de Brasil (2015-2023)].Revista panamericana de salud publica = Pan American journal of public health · 2026Article
- Competitive Viral Interference Controls Arbovirus Co-Transmission in Aedes aegypti.Scientific reports · 2025Article
- Spatio-temporal analysis of the distribution and co-circulation of dengue, chikungunya, and Zika in Medellín, Colombia, from 2013 to 2021.PLoS neglected tropical diseases · 2025Article
- Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study.BMC infectious diseases · 2025Article
- From infectious diseases to chronic diseases: the paradigm shift of spatial epidemiology in disease prevention and control.Frontiers in public health · 2025Review
- The Temporal Order of Mixed Viral Infections Matters: Common Events That Are Neglected in Plant Viral Diseases.Viruses · 2024Review
- Spatial and Temporal Dynamics of Chikungunya Incidence in Brazil and the Impact of Social Vulnerability: A Population-Based and Ecological Study.Diseases (Basel, Switzerland) · 2024Article
- DENV-2 Outbreak Associated With Cosmopolitan Genotype Emergence in Western Brazilian Amazon.Bioinformatics and biology insights · 2024Article
- Acceptability of a hypothetical dengue vaccine and the potential impact of dengue vaccination on personal vector control behavior: a qualitative study in Fortaleza, Brazil.BMC public health · 2023Article
- Zika, chikungunya and co-occurrence in Brazil: space-time clusters and associated environmental-socioeconomic factors.Scientific reports · 2023Article
- Democratizing Public Health: Participatory Policymaking Institutions, Mosquito Control, and Zika in the Americas.Tropical medicine and infectious disease · 2023Article
- High-risk spatial clusters for Zika, dengue, and chikungunya in Rio de Janeiro, Brazil.Revista de saude publica · 2023Article
- Dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean: a systematic review.Revista panamericana de salud publica = Pan American journal of public health · 2023Review
- Rapid and Non-Invasive Detection ofViruses · 2022Article
- Report of Mosquito Vectors of Arboviruses from a Federal Conservation Unit in the Atlantic Forest, Rio de Janeiro State, Brazil.Life (Basel, Switzerland) · 2022Article
- Entomo-virological surveillance followed by serological active survey of symptomatic individuals is helpful to identify hotspots of early arbovirus transmission.Frontiers in public health · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mosquito-borne viruses dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV), now co-endemic in the Americas, pose growing threats to health worldwide. However, it remains unclear whether there exist interactions between these viruses that could shape their epidemiology. This study advances knowledge by assessing the transmission dynamics of co-circulating DENV, ZIKV, and CHIKV in the city of Fortaleza, Brazil. Spatiotemporal transmission dynamics of DENV, ZIKV, and CHIKV were analyzed using georeferenced data on over 210,000 reported cases from 2011 to 2017 in Fortaleza, Brazil. Local spatial clustering tests and space-time scan statistics were used to compare transmission dynamics across all years. The transmission of co-circulating viruses in 2016 and 2017 was evaluated at fine spatial and temporal scales using a measure of spatiotemporal dependence, the τ-statistic. Results revealed differences in the diffusion of CHIKV compared to previous DENV epidemics and spatially distinct transmission of DENV/ZIKV and CHIKV during the period of their co-circulation. Significant spatial clustering of viruses of the same type was observed within 14-day time intervals at distances of up to 6.8 km (p<0.05). These results suggest that arbovirus risk is not uniformly distributed within cities during co-circulation. Findings may guide outbreak preparedness and response efforts by highlighting the clustered nature of transmission of co-circulating arboviruses at the neighborhood level. The potential for competitive interactions between the arboviruses should be further investigated.
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