Evidence map›Paper›PMID 33104519›Full record

Trial reportAging2020

Aerobic exercise induces tumor suppressor p16

Jinfu Wu, I-Shiung Cheng, Suchada Saovieng, Wei-Horng Jean, Chung-Lan Kao, Yung-Yang Liu, Chih-Yang Huang, Tania Xu Yar Lee, John L Ivy, Chia-Hua Kuo

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jinfu WuLaboratory of Regenerative Medicine in Sports Science, School of Physical Education and Sports Science, South China Normal University, Guangzhou, China.
I-Shiung ChengLaboratory of Exercise Nutrition, National Taichung University of Education, Taichung, Taiwan.
Suchada SaoviengLaboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan.
Wei-Horng JeanLaboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan.
Chung-Lan KaoDepartment of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan.
Yung-Yang LiuDepartment of Chest Medicine, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan.
Chih-Yang HuangChinese Medicine, Hualien Tzu Chi Hospital, Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan.
Tania Xu Yar LeeLaboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan.
John L IvyDepartment of Kinesiology and Health Education, The University of Texas at Austin, TX 78712, USA.
Chia-Hua KuoLaboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan.
University of Taipei · TWMahidol University · THNational Taichung University of Education · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerobic exercise induces oxidative stress and DNA damage, nevertheless, lowers cancer incidence. It remains unclear how genetic stability is maintained under this condition. Here, we examined the dynamic change of the tumor suppressor p16

Indexed as

ExerciseMuscle ContractionAntigens, CDAntigens, Differentiation, MyelomonocyticBicyclingCD163 AntigenCross-Over StudiesCyclin-Dependent Kinase Inhibitor p16DNA DamageDown-RegulationEndothelial Progenitor CellsGinsenosidesHumansInterleukin-10MacrophagesMaleAntigens, CDAntigens, Differentiation, MyelomonocyticCD163 AntigenCDKN2A protein, humanCyclin-Dependent Kinase Inhibitor p16ginsenoside Rg1GinsenosidesIL10 protein, humanInterleukin-10Receptors, Cell SurfaceVascular Endothelial Growth Factor AVEGFA protein, humancancercell cycle arrestskeletal muscletumor

Identifiers

PMID33104519
PMCPMC7655215
OpenAlexW3093583457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.