Evidence map›Paper›PMID 33104504›Full record

ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2021

Patient-Preferred Prosthetic Ankle-Foot Alignment for Ramps and Level-Ground Walking.

Max K Shepherd, Ann M Simon, Joey Zisk, Levi J Hargrove

Registry-linked trialAbstract read
In one paragraph

Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07530601 (Multidimensional Assessment of a New Ankle-Foot Prosthesis in Daily Use), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07530601 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multidimensional Assessment of a New Ankle-Foot Prosthesis in Daily Use: User Comfort, Safety, and Biomechanical Performance

TypeinterventionalSponsorVrije Universiteit BrusselRan2026 to 2027Enrolled120ConditionsLower-Limb AmputationArmsNew Articulated Prosthetic Foot, Current Prosthetic foot
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Improving Device Testing Efficiency in Prosthetic Research: The Impact of an Automated Robustness Testing Protocol.Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Understanding patient preference in prosthetic ankle stiffness.Journal of neuroengineering and rehabilitation · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Max K Shepherd
Ann M Simon
Joey Zisk
Levi J Hargrove

Funding

Intuitive Control of a Hybrid Prosthetic Leg During AmbulationR01HD079428 · NICHD · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI HARGROVE, LEVI JOHN · 2014 to 2022
$5.6M
ACL HHS 90REGE0003NICHD NIH HHS R01 HD079428
6 · The paper itself

Abstract

Patient preference of lower limb prosthesis behavior informally guides clinical decision making, and may become increasingly important for tuning new robotic prostheses. However, the processes for quantifying preference are still being developed, and the strengths and weaknesses of preference are not adequately understood. The present study sought to characterize the reliability (consistency) of patient preference of alignment during level-ground walking, and determine the patient-preferred ankle angle for ascent and descent of a 10° ramp, with implications for the design and control of robotic prostheses. Seven subjects with transtibial amputation walked over level ground, and ascended and descended a 10° ramp on a semi-active prosthetic ankle capable of unweighted repositioning in dorsiflexion and plantarflexion. Preferred ankle angle was measured with an adaptive forced-choice psychophysics paradigm, in which subjects walked on a randomized static ankle angle and reported whether they would prefer the ankle to be dorsiflexed or plantarflexed. Subjects had reliable preferences for alignment during level-ground walking, with deviations of 1.5° from preference resulting in an 84% response rate preferring changes toward the preference. Relative to level walking, subjects preferred 7.8° (SD: 4.8°) of dorsiflexion during ramp ascent, and 5.3° (SD: 3.8°) plantarflexion during ramp descent. As the ankle angle better matched the ramp angle, socket pressures and tibial progression (shank pitch) both more closely mirrored those during level walking. These findings provide baseline behaviors for prosthetic ankles capable of adapting to slopes based on patient preference, and provide strong evidence that people with transtibial amputation can finely perceive ankle alignment.

Indexed as

AmputeesArtificial LimbsAnkleAnkle JointBiomechanical PhenomenaGaitHumansProsthesis DesignReproducibility of ResultsWalking

Identifiers

PMID33104504
PMCPMC8060022

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.