SynthesisCanadian journal of psychiatry. Revue canadienne de psychiatrie2020
Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis.
Synthesis in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Canadian Network for Mood and Anxiety Treatments 2024 Clinical Practice Guideline for the Management of Perinatal Mood, Anxiety, and Related Disorders: Guide de pratique 2024 du Canadian Network for Mood and Anxiety Treatments pour le traitement des troubles de l'humeur, des troubles anxieux et des troubles connexes périnatals.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2025Guideline
- Tools for screening maternal mental health conditions in primary care settings in sub-Saharan Africa: systematic review.Frontiers in public health · 2024Pooled it
- Prevalence of Postpartum Depression Based on Diagnostic Interviews: A Systematic Review and Meta-Analysis.Depression and anxiety · 2023Pooled it
- Mom Supporting Mom: Effective Peer Support Intervention for Women with Postpartum Psychological Distress.Psychosocial intervention · 2025Trial
- Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study.International journal of nursing studies advances · 2025Article
- Antidepressants and hypertensive disorders in pregnancy: a retrospective cohort analysis.Frontiers in psychiatry · 2025Article
- Association of Antepartum and Postpartum Air Pollution Exposure With Postpartum Depression in Southern California.JAMA network open · 2023Article
- Gestational anemia and maternal antenatal and postpartum psychological distress in a prospective FinnBrain Birth Cohort Study.BMC pregnancy and childbirth · 2022Article
- Scalable Screening and Treatment Response Monitoring for Perinatal Depression in Low- and Middle-Income Countries.International journal of environmental research and public health · 2021Article
- Multimodal Acoustic-Linguistic Machine Learning for Postpartum Depression Screening Using the Edinburgh Postnatal Depression Scale.Women's health reports (New Rochelle, N.Y.)Article
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Authors and funding
51 authors.
Funding
Abstract
objectiveThe Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported "feelings consistent with postpartum depression" based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS-5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).
methodsWe searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with data sets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual participant data meta-analysis to estimate pooled percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.
resultsA total of 3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.
conclusionsPrevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.
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