Evidence map›Paper›PMID 33104268›Full record

ArticleAlcoholism, clinical and experimental research2020

Depression, Alcoholics Anonymous Involvement, and Daily Drinking Among Patients with co-occurring Conditions: A Longitudinal Parallel Growth Mixture Model.

Noel Vest, Alex Sox-Harris, Mark Ilgen, Keith Humphreys, Christine Timko

Open access · bronzeAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Noel VestFrom the, Department of Psychiatry and Behavioral Sciences (NAV, KH, CT), Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-8014-9726
Alex Sox-HarrisVeterans Affairs Palo Alto Health Care System, (AHSH, KH, CT), Palo Alto, California, USA.
Mark IlgenDepartment of Psychiatry, (MI), University of Michigan, Ann Arbor, Michigan, USA.
Keith HumphreysFrom the, Department of Psychiatry and Behavioral Sciences (NAV, KH, CT), Stanford University School of Medicine, Stanford, California, USA.
Christine TimkoFrom the, Department of Psychiatry and Behavioral Sciences (NAV, KH, CT), Stanford University School of Medicine, Stanford, California, USA.
VA Palo Alto Health Care System · USStanford Medicine · USUniversity of Michigan · US

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
HSR&D Research Career Scientist AwardIK6HX002841 · VA · VETERANS HEALTH ADMINISTRATION · PI MARK A. ILGEN · 2020 to 2026
–
Health Services Research and Development RCS 14-141Health Services Research and Development RSC 19-333HSRD VA IAC 09-055HSRD VA IK6 HX002841HSRD VA RCS 00-001HSRD VA RCS 14-232NIDA NIH HHS T32 DA035165NIDA NIH HHS T32DA035165
6 · The paper itself

Abstract

backgroundPatients with cooccurring mental health and substance use disorders often find it difficult to sustain long-term recovery. One predictor of recovery may be how depression symptoms and Alcoholics Anonymous (AA) involvement influence alcohol consumption during and after inpatient psychiatric treatment. This study utilized a parallel growth mixture model to characterize the course of alcohol use, depression, and AA involvement in patients with cooccurring diagnoses.

methodsParticipants were adults with cooccurring disorders (n = 406) receiving inpatient psychiatric care as part of a telephone monitoring clinical trial. Participants were assessed at intake, 3-, 9-, and 15-month follow-up.

resultsA 3-class solution was the most parsimonious based upon fit indices and clinical relevance of the classes. The classes identified were high AA involvement with normative depression (27%), high stable depression with uneven AA involvement (11%), and low AA involvement with normative depression (62%). Both the low and high AA classes reduced their drinking across time and were drinking at less than half their baseline levels at all follow-ups. The high stable depression class reported an uneven pattern of AA involvement and drank at higher daily frequencies across the study timeline. Depression symptoms and alcohol use decreased substantially from intake to 3 months and then stabilized for 90% of patients with cooccurring disorders following inpatient psychiatric treatment.

conclusionsThese findings can inform future clinical interventions among patients with cooccurring mental health and substance use disorders. Specifically, patients with more severe symptoms of depression may benefit from increased AA involvement, whereas patients with less severe symptoms of depression may not.

Indexed as

Alcoholics AnonymousAdultAlcohol DrinkingAlcoholismDepressionFemaleHumansLongitudinal StudiesMaleMiddle AgedModels, StatisticalTreatment OutcomeAlcoholics Anonymous InvolvementAlcohol UseCooccurring PatientsDepressionLongitudinal Growth Mixture Model

Identifiers

PMID33104268
PMCPMC7863278
OpenAlexW3093755706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.