Evidence map›Paper›PMID 33104248›Full record

ArticleMagnetic resonance in medicine2021

Quantitative and simultaneous measurement of oxygen consumption rates in rat brain and skeletal muscle using

Hannes M Wiesner, Dávid Z Balla, Klaus Scheffler, Kâmil Uğurbil, Xiao-Hong Zhu, Wei Chen, Kâmil Uludağ, Rolf Pohmann

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. QuantitativeMagnetic resonance in medicine · 2024
    Article
  7. Article
  8. Article
  9. Zero Echo TimeMetabolites · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Hannes M WiesnerHigh-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.ORCID 0000-0003-3046-4933
Dávid Z BallaHigh-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.ORCID 0000-0003-2772-8950
Klaus SchefflerHigh-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.ORCID 0000-0001-6316-8773
Kâmil UğurbilCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-8475-9334
Xiao-Hong ZhuCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.
Wei ChenCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-9608-1444
Kâmil UludağTechna Institute and Koerner Scientist in MR Imaging, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-2813-5930
Rolf PohmannHigh-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.ORCID 0000-0002-6137-9590
University of Minnesota · USMax Planck Institute for Biological Cybernetics · DEUniversity Health Network · CA

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger · 2019 to 2026
$11.7M
Breaking Spatiotemporal Barriers of MR Imaging Technologies to Study Human Brain Function and NeuroenergeticsU01EB026978 · NIBIB · UNIVERSITY OF MINNESOTA · PI CHEN, WEI, ZHU, XIAO-HONG · 2018 to 2022
$6.4M
Integrated fMRI Methods to Study Neurophysiology and Circuit Dynamics at Laminar and Columnar LevelR01MH111413 · NIMH · UNIVERSITY OF MINNESOTA · PI CHEN, WEI · 2016 to 2020
$4.4M
Development of Quantitative Deuterium MRS Imaging for Human Brain Tumor Application at Ultrahigh FieldR01CA240953 · NCI · UNIVERSITY OF MINNESOTA · PI CHEN, WEI, LIANG, ZHI-PEI · 2019 to 2025
$2.7M
Quantitative and Non-invasive Imaging of Oxygen Metabolism in Human BrainR01NS070839 · NINDS · UNIVERSITY OF MINNESOTA · PI ZHU, XIAO-HONG · 2010 to 2014
$2.2M
NCI NIH HHS R01 CA240953NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U01 EB026978NIMH NIH HHS R01 MH111413NINDS NIH HHS R01 NS070839
6 · The paper itself

Abstract

purposeOxygen-17 (

methodsDuring and after inhalations of

resultsCerebral metabolic rate of oxygen consumption was 1.97 ± 0.19 μmol/g/min on average. The resting metabolic rate of oxygen consumption in skeletal muscle was 0.32 ± 0.12 μmol/g/min and >6 times lower than cerebral metabolic rate of oxygen consumption. Global oxygen consumed by the body was 24.2 ± 3.6 mL O

conclusionWe have evaluated the feasibility of

Indexed as

Cerebrovascular CirculationOxygen ConsumptionAnimalsBrainMuscle, SkeletalOxygenRatsOxygen17O MRSI of H217Ocerebral blood flow (CBF)cerebral metabolic rate of oxygen (CMRO2)mitochondrial watermuscle resting metabolic rate of oxygen consumptionskeletal muscle metabolismtotal body oxygen consumption (VO2)

Identifiers

PMID33104248
PMCPMC7775343
OpenAlexW3094581945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.