Evidence map›Paper›PMID 33104015›Full record

ArticleJournal of medical Internet research2020

The Role of Social Media in Enhancing Clinical Trial Recruitment: Scoping Review.

Ida Darmawan, Caitlin Bakker, Tabetha A Brockman, Christi A Patten, Milton Eder

Abstract readScoping Review
In one paragraph

Article in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  9. Article
  10. Educators, Not Influencers: Health Content Creator Perspectives on Research Recruitment Collaboration.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Pharmacomicrobiomics.Clinical pharmacology and therapeutics · 2025
    Review
  18. Article
  19. Review
  20. Observational

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ida DarmawanHubbard School of Journalism and Mass Communication, University of Minnesota, Minneapolis, MN, United States.ORCID 0000-0002-2178-3740
Caitlin BakkerHealth Sciences Libraries, University of Minnesota, Minneapolis, MN, United States.ORCID 0000-0003-4154-8382
Tabetha A BrockmanDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0003-4008-4395
Christi A PattenDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, United States.ORCID 0000-0002-7194-8160
Milton EderDepartment of Family Medicine & Community Health, University of Minnesota, Minneapolis, MN, United States.ORCID 0000-0002-4036-6491

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
NCATS NIH HHS UL1 TR002377NCATS NIH HHS UL1 TR002494
6 · The paper itself

Abstract

backgroundRecruiting participants into clinical trials continues to be a challenge, which can result in study delay or termination. Recent studies have used social media to enhance recruitment outcomes. An assessment of the literature on the use of social media for this purpose is required.

objectiveThis study aims to answer the following questions: (1) How is the use of social media, in combination with traditional approaches to enhance clinical trial recruitment and enrollment, represented in the literature? and (2) Do the data on recruitment and enrollment outcomes presented in the literature allow for comparison across studies?

methodsWe conducted a comprehensive literature search across 7 platforms to identify clinical trials that combined social media and traditional methods to recruit patients. Study and participant characteristics, recruitment methods, and recruitment outcomes were evaluated and compared.

resultsWe identified 2371 titles and abstracts through our systematic search. Of these, we assessed 95 full papers and determined that 33 studies met the inclusion criteria. A total of 17 studies reported enrollment outcomes, of which 9 achieved or exceeded their enrollment target. The proportion of participants enrolled from social media in these studies ranged from 0% to 49%. Across all 33 studies, the proportion of participants recruited and enrolled from social media varied greatly. A total of 9 studies reported higher enrollment rates from social media than any other methods, and 4 studies reported the lowest cost per enrolled participant from social media.

conclusionsWhile the assessment of the use of social media to improve clinical trial participation is hindered by reporting inconsistencies, preliminary data suggest that social media can increase participation and reduce per-participant cost. The adoption of consistent standards for reporting recruitment and enrollment outcomes is required to advance our understanding and use of social media to support clinical trial success.

Indexed as

Clinical Trials as TopicFemaleHumansMaleSocial Mediaclinical trialenrollment methodsrecruitment methodsreviewsocial media

Identifiers

PMID33104015
PMCPMC7652693

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.