Evidence map›Paper›PMID 33103840›Full record

ArticleHIV medicine2021

HIV prevalence and HIV clinical outcomes of transgender and gender-diverse people in England.

P D Kirwan, M Hibbert, M Kall, K Nambiar, M Ross, S Croxford, S Nash, L Webb, A Wolton, V C Delpech

Open access · hybridAbstract read
In one paragraph

Article in HIV medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Sexually transmitted infections · 2025
    Article
  2. Article
  3. Prevalence of cancer risk factors among transgender and gender diverse individuals: a cross-sectional analysis using UK primary care data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

P D KirwanBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0001-6904-0500
M HibbertBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0002-1759-455X
M KallBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0001-6971-427X
K NambiarBrighton and Sussex University Hospitals NHS Trust, Brighton, UK.ORCID 0000-0001-8591-0203
M RosscliniQ, London, UK.
S CroxfordBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0003-2220-623X
S NashBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0002-7717-6982
L WebbLGBT Foundation, Manchester, UK.
A WoltonChelsea and Westminster Hospital NHS Trust, London, UK.
V C DelpechBlood Safety, Hepatitis, Sexually Transmitted Infections and HIV Division, Public Health England, London, UK.ORCID 0000-0002-9952-8109
Public Health England · GBChelsea and Westminster Hospital NHS Foundation Trust · GBClinks (United Kingdom) · GBLGBT Foundation · GBUniversity Hospitals Sussex NHS Foundation Trust · GBUniversity of Cambridge · GB

Funding

Medical Research Council MC_UU_00002/11
6 · The paper itself

Abstract

objectivesWe provide the first estimate of HIV prevalence among trans and gender-diverse people living in England and compare outcomes of people living with HIV according to gender identity.

methodsWe analysed a comprehensive national HIV cohort and a nationally representative self-reported survey of people accessing HIV care in England (Positive Voices). Gender identity was recorded using a two-step question co-designed with community members and civil society. Responses were validated by clinic follow-up and/or self-report. Population estimates were obtained from national government offices.

resultsIn 2017, HIV prevalence among trans and gender-diverse people was estimated at 0.46-4.78 per 1000, compared with 1.7 (95% credible interval: 1.6-1.7) in the general population. Of 94 885 people living with diagnosed HIV in England, 178 (0.19%) identified as trans or gender-diverse. Compared with cisgender people, trans and gender-diverse people were more likely to be London residents (57% vs. 43%), younger (median age 42 vs. 46 years), of white ethnicity (61% vs. 52%), under psychiatric care (11% vs. 4%), to report problems with self-care (37% vs. 13%), and to have been refused or delayed healthcare (23% vs. 11%). Antiretroviral uptake and viral suppression were high in both groups.

conclusionsHIV prevalence among trans and gender-diverse people living in England is relatively low compared with international estimates. Furthermore, no inequalities were observed with regard to HIV care. Nevertheless, trans and gender-diverse people with HIV report poorer mental health and higher levels of discrimination compared with cisgender people.

Indexed as

HIV InfectionsTransgender PersonsAdultFemaleGender IdentityHumansMalePrevalenceSurveys and Questionnairesgender identityHIVpatient careprevalencetransgender people

Identifiers

PMID33103840
PMCPMC7613967
OpenAlexW3093641687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.