Evidence map›Paper›PMID 33103616›Full record

ArticleJournal of biomolecular structure & dynamics2022

Natural phyto, compounds as possible noncovalent inhibitors against SARS-CoV2 protease: computational approach.

Joyce Oloaigbe Ogidigo, Emmanuel A Iwuchukwu, Collins U Ibeji, Okiemute Okpalefe, Mahmoud E S Soliman

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular structure & dynamics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Potential ofBioMed research international · 2022
    Pooled it
  2. Article
  3. Therapeutic Potential of Momordicine I fromInternational journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. RSC advances · 2022
    Article
  9. Article
  10. The Antimicrobial Potential of the Neem TreeFrontiers in pharmacology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

Joyce Oloaigbe OgidigoBio-resources Development Centre, National Biotechnology Development Agency, Abuja, Nigeria.
Emmanuel A IwuchukwuMolecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu Natal, Durban, South Africa.
Collins U IbejiCatalysis and Peptide Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Okiemute OkpalefeDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, Enugu, Nigeria.
Mahmoud E S SolimanMolecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu Natal, Durban, South Africa.
University of Nigeria · NGUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, there is no cure or vaccine for the devastating new highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has affected people globally. Herein, we identified potent phytocompounds from two antiviral plants

Indexed as

COVID-19 Drug TreatmentPeptide HydrolasesHumansMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsRNA, ViralSARS-CoV-2Peptide HydrolasesProtease InhibitorsRNA, ViralMMGBAmolecular dynamics simulationsnatural phytocompoundsSARS-CoV-2

Identifiers

PMID33103616
PMCPMC7596894
OpenAlexW3093972988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.