ArticleAmerican journal of physiology. Renal physiology2020
Beyond the tubule: pathological variants of
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Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 27 citations in OpenAlex.
- Review
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- Proximity Labeling Reveals How Lrp2 Interacts with the Endocytic Machine.Journal of proteome research · 2026Article
- Nonprogressive Nephrotic Range Proteinuria Because of Indirect Cubilin Dysfunction.Kidney international reports · 2026Article
- Antiproteinuric effect of dapagliflozin attenuates tubule-interstitial injury development in subclinical acute kidney injury animal model.Frontiers in pharmacology · 2026Article
- Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice.Scientific reports · 2025Article
- Methylseq, single-nuclei RNAseq, and discovery proteomics identify pathways associated with nephron-deficit CKD in the HSRA rat model.American journal of physiology. Renal physiology · 2025Article
- Crosstalk between glomeruli and tubules.Nature reviews. Nephrology · 2025Review
- Megalin: A Sidekick or Nemesis of the Kidney?Journal of the American Society of Nephrology : JASN · 2025Review
- Microglia-Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- 5-Hydroxytryptamine 1F Receptor Agonist Lasmiditan Differentially Regulates Successful Repair and Failed Repair Genes in a Mouse Model of Acute Kidney Injury.ACS pharmacology & translational science · 2024Article
- Megalin Knockout Reduces SGLT2 Expression and Sensitizes to Western Diet-induced Kidney Injury.Function (Oxford, England) · 2024Article
- Prevalence of kidney health genetic variants in adults with sickle cell nephropathy.British journal of haematology · 2024Article
- Noninvasive assessment of organ-specific and shared pathways in multi-organ fibrosis using T1 mapping.Nature medicine · 2024Article
- The multifaceted links between hearing loss and chronic kidney disease.Nature reviews. Nephrology · 2024Review
- Low molecular weight proteinuria, congenital myopia and hearing loss in a 10-year-old boy: Answers.Pediatric nephrology (Berlin, Germany) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 15 institutions in 6 countries.
Jennifer R CharltonDivision of Nephrology, Department of Pediatrics, University of Virginia, Charlottesville, Virginia.
Weizhen TanDivision of Nephrology, Massachusetts General Hospital for Children, Boston, Massachusetts.
Ghaleb DaoukDivision of Nephrology, Massachusetts General Hospital for Children, Boston, Massachusetts.
Lisa TeotDepartment of Pathology, Boston Children's Hospital, Boston, Massachusetts.
Seymour RosenDepartment of Pathology, Boston Children's Hospital, Boston, Massachusetts.
Kevin M BennettDepartment of Radiology, Washington University in Saint Louis, St. Louis, Missouri.
Aleksandra CwiekDivision of Nephrology, Department of Pediatrics, University of Virginia, Charlottesville, Virginia.
Sejin NamDepartment of Physics, University of Hawai'i at Manoa, Manoa, Hawai'i.
Francesco EmmaDivision of Nephrology, Department of Pediatric Subspecialties, Bambino Gesù Children's Hospital- Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy.
François JouretGroupe Interdisciplinaire de Génoprotéomique Appliquée, Unit of Cardiovascular Sciences, University of Liège, Liège, Belgium.
João Paulo OliveiraService of Medical Genetics, São João University Hospital Centre and Faculty of Medicine, University of Porto and i3S-Institute for Health Research and Innovation, Porto, Portugal.
Lisbeth TranebjærgDepartment of Clinical Genetics, Rigshospitalet/The Kennedy Centre, Copenhagen, Denmark.
Carina FrykholmDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Shrikant ManeDepartment of Genetics, Yale University School of Medicine, New Haven, Connecticut.
Friedhelm HildebrandtDepartment of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Tarak SrivastavaChildren's Mercy Hospital, Kansas City, Missouri.
Tina StormDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Erik Ilsø ChristensenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Rikke NielsenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Aarhus University · DKMassachusetts General Hospital · USUniversity of Virginia · USBambino Gesù Children's Hospital · ITBeth Israel Deaconess Medical Center · USBoston Children's Hospital · USHarvard University · USi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTMercy Hospital · USRigshospitalet · DKUniversity of Hawaiʻi at Mānoa · USUniversity of Liège · BEUppsala University · SEWashington University in St. Louis · USYale University · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MRenal Physiology and Phenotyping CoreP30DK079310 · NIDDK · YALE UNIVERSITY · PI SOMLO, STEFAN · 2008 to 2022
$16.8MYale Center for Mendelian DisordersU54HG006504 · NHGRI · YALE UNIVERSITY · PI GERSTEIN, MARK BENDER, GUNEL, MURAT · 2012 to 2015
$11.0MIdentification and function of new genes causing childhood nephrotic syndromeR01DK076683 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HILDEBRANDT, FRIEDHELM · 2007 to 2021
$5.3M94 TESLA MR SCANNER FOR MURINE IMAGING: IMAGINGS10RR019911 · NCRR · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI BERR, STUART S · 2005 to 2005
$2.0MComprehensive MRI-based evaluation of human renal microstructureR01DK111861 · NIDDK · UNIVERSITY OF VIRGINIA · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2020
$1.8MNoninvasive MRI techniques to detect pathology in murine models of renal diseaseR01DK110622 · NIDDK · WASHINGTON UNIVERSITY · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2019
$1.0MNCATS NIH HHS UL1 TR001863NCRR NIH HHS S10 RR019911NHGRI NIH HHS U54 HG006504NIDDK NIH HHS P30 DK079310NIDDK NIH HHS R01 DK076683NIDDK NIH HHS R01 DK110622NIDDK NIH HHS R01 DK111861NIH HHS 1S10RR019911-01NIH HHS DK0668306NIH HHS R01DK110622NIH HHS R01DK111861
Abstract
Pathogenic variants in the
Indexed as
Genetic Predisposition to DiseaseGenetic VariationAdolescentAdultAnimalsChildChild, PreschoolFemaleHumansKidney GlomerulusLow Density Lipoprotein Receptor-Related Protein-2MaleMiceMice, KnockoutMiddle AgedRenal Insufficiency, ChronicLow Density Lipoprotein Receptor-Related Protein-2LRP2 protein, humanLrp2 protein, mousecationic ferritin-enhanced magnetic resonance imagingglomerular numberkidney disease etiologymegalinnephron lossproximal tubule
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.