Evidence map›Paper›PMID 33103017›Full record

ArticleCurrent opinion in physiology2020

Auditory brainstem development and plasticity.

María Eulalia Rubio

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  2. Article
  3. Time Course of Activity-Dependent Changes in Auditory Nerve Synapses Reveals Multiple Underlying Cellular Mechanisms.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

María Eulalia RubioDepartments of Neurobiology and Otolaryngology, University of Pittsburgh, School of Medicine, BST3 Building, room #10016, 3501 Fifth Venue, Pittsburgh, PA, 15261.
University of Pittsburgh · US

Funding

Mechanisms of hypersensitivity to sound-induced cochlear damageR01DC013048 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Maria-Eulalia Rubio-Valero · 2013 to 2026
$6.8M
Mechanisms of hypersensitivity to sound-induced cochlear damageR56DC013048 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RUBIO-VALERO, MARIA-EULALIA · 2018 to 2018
$304k
NIDCD NIH HHS R01 DC013048NIDCD NIH HHS R56 DC013048
6 · The paper itself

Abstract

During development and adulthood, the normal activity of the auditory nerve plays a critical role in the maintenance of both fundamental structural, molecular, and functional parameters of auditory nerve synapses, and the postsynaptic excitatory or inhibitory neurons within the cochlear nucleus (CN). In addition, normal activity within the synaptic circuits of the CN is key to developing and maintaining appropriate synapse connectivity as well as the initiation of binaural sound processing in the superior olivary complex (SOC). Development plays a critical role in the proper neuronal connectivity and establishes a topographic map along the entire auditory pathway. Furthermore, evidence shows that neurons and synaptic circuits in the auditory brainstem are not hard-wired, but instead are plastic in response to hearing deficits. Whether this plasticity in response to hearing loss is compensatory or pathological is still unknown.

Indexed as

cellular mechanismscochlear nucleusglial cellshearing losssuperior olivary complexsynapses

Identifiers

PMID33103017
PMCPMC7583349
OpenAlexW3041834191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.